A Rare Case of Cladophialophora bantiana Intracranial Infection: Highlighting the Utility of Next-Generation Sequencing in Diagnosis
Cladophialophora bantiana is a dematiaceous fungi and the most common cause of cerebral phaeohyphomycosis. Here, we report a rare case of cerebral ventriculitis with development of a cerebral abscess due to C. bantiana diagnosed by cell-free DNA next-generation sequencing. Noninvasive diagnostics le...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2024-01-01
|
| Series: | Case Reports in Transplantation |
| Online Access: | http://dx.doi.org/10.1155/2024/8892177 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832569099643781120 |
|---|---|
| author | Melissa Whitman Nicole Vissichelli |
| author_facet | Melissa Whitman Nicole Vissichelli |
| author_sort | Melissa Whitman |
| collection | DOAJ |
| description | Cladophialophora bantiana is a dematiaceous fungi and the most common cause of cerebral phaeohyphomycosis. Here, we report a rare case of cerebral ventriculitis with development of a cerebral abscess due to C. bantiana diagnosed by cell-free DNA next-generation sequencing. Noninvasive diagnostics led to earlier disease identification and initiation of antifungal therapy, which has the potential to reduce mortality in this highly fatal disease. |
| format | Article |
| id | doaj-art-1e5ea9de809d4642b5751c132f3541b1 |
| institution | Kabale University |
| issn | 2090-6951 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Transplantation |
| spelling | doaj-art-1e5ea9de809d4642b5751c132f3541b12025-02-02T23:07:58ZengWileyCase Reports in Transplantation2090-69512024-01-01202410.1155/2024/8892177A Rare Case of Cladophialophora bantiana Intracranial Infection: Highlighting the Utility of Next-Generation Sequencing in DiagnosisMelissa Whitman0Nicole Vissichelli1Division of Infectious DiseasesDivision of Infectious DiseasesCladophialophora bantiana is a dematiaceous fungi and the most common cause of cerebral phaeohyphomycosis. Here, we report a rare case of cerebral ventriculitis with development of a cerebral abscess due to C. bantiana diagnosed by cell-free DNA next-generation sequencing. Noninvasive diagnostics led to earlier disease identification and initiation of antifungal therapy, which has the potential to reduce mortality in this highly fatal disease.http://dx.doi.org/10.1155/2024/8892177 |
| spellingShingle | Melissa Whitman Nicole Vissichelli A Rare Case of Cladophialophora bantiana Intracranial Infection: Highlighting the Utility of Next-Generation Sequencing in Diagnosis Case Reports in Transplantation |
| title | A Rare Case of Cladophialophora bantiana Intracranial Infection: Highlighting the Utility of Next-Generation Sequencing in Diagnosis |
| title_full | A Rare Case of Cladophialophora bantiana Intracranial Infection: Highlighting the Utility of Next-Generation Sequencing in Diagnosis |
| title_fullStr | A Rare Case of Cladophialophora bantiana Intracranial Infection: Highlighting the Utility of Next-Generation Sequencing in Diagnosis |
| title_full_unstemmed | A Rare Case of Cladophialophora bantiana Intracranial Infection: Highlighting the Utility of Next-Generation Sequencing in Diagnosis |
| title_short | A Rare Case of Cladophialophora bantiana Intracranial Infection: Highlighting the Utility of Next-Generation Sequencing in Diagnosis |
| title_sort | rare case of cladophialophora bantiana intracranial infection highlighting the utility of next generation sequencing in diagnosis |
| url | http://dx.doi.org/10.1155/2024/8892177 |
| work_keys_str_mv | AT melissawhitman ararecaseofcladophialophorabantianaintracranialinfectionhighlightingtheutilityofnextgenerationsequencingindiagnosis AT nicolevissichelli ararecaseofcladophialophorabantianaintracranialinfectionhighlightingtheutilityofnextgenerationsequencingindiagnosis AT melissawhitman rarecaseofcladophialophorabantianaintracranialinfectionhighlightingtheutilityofnextgenerationsequencingindiagnosis AT nicolevissichelli rarecaseofcladophialophorabantianaintracranialinfectionhighlightingtheutilityofnextgenerationsequencingindiagnosis |