Unlocking the epigenetic code: new insights into triple-negative breast cancer

Unlocking the epigenetic code: new insights into triple-negative breast cancer

Triple-negative breast cancer (TNBC) is a highly aggressive and clinically challenging subtype of breast cancer, lacking the expression of estrogen receptor (ER), progesterone receptor (PR), and HER2/neu. The absence of these receptors limits therapeutic options necessitating the exploration of nove...

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Bibliographic Details
Main Authors: Gowthami Mahendran, Ann Dharshika Shangaradas, Ricardo Romero-Moreno, Nadeeshika Wickramarachchige Dona, S. H. G. Sumudu Sarasija, Sumeth Perera, Gayathri N. Silva
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Oncology
Subjects:
triple-negative breast cancer (TNBC)
epigenetic modifications
DNA methylation
histone deacetylase inhibitors (HDACi)
microRNA (miRNA)
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1499950/full
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https://www.frontiersin.org/articles/10.3389/fonc.2024.1499950/full

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