Mediators of Inflammation in Polycystic Ovary Syndrome in Relation to Adiposity

Polycystic ovary syndrome (PCOS) is a common endocrine disorder in women of reproductive age group and is associated with a higher cardiovascular risk. Obesity, mainly visceral adiposity, is prevalent in patients with PCOS. Obesity is associated with low-grade inflammation and raised inflammatory cy...

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Main Authors: Thozhukat Sathyapalan, Stephen L. Atkin
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2010/758656
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author Thozhukat Sathyapalan
Stephen L. Atkin
author_facet Thozhukat Sathyapalan
Stephen L. Atkin
author_sort Thozhukat Sathyapalan
collection DOAJ
description Polycystic ovary syndrome (PCOS) is a common endocrine disorder in women of reproductive age group and is associated with a higher cardiovascular risk. Obesity, mainly visceral adiposity, is prevalent in patients with PCOS. Obesity is associated with low-grade inflammation and raised inflammatory cytokines, both of which are also described in patients with PCOS. In this paper, the potential relationships between fat distribution, adipocyte dysfunction and, altered inflammatory markers in patients with PCOS have been discussed.
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series Mediators of Inflammation
spelling doaj-art-1e47ced95770422bbd15c177c25844f42025-02-03T01:31:30ZengWileyMediators of Inflammation0962-93511466-18612010-01-01201010.1155/2010/758656758656Mediators of Inflammation in Polycystic Ovary Syndrome in Relation to AdiposityThozhukat Sathyapalan0Stephen L. Atkin1Academic Endocrinology, Diabetes and Metabolism, Hull York Medical School, Michael White Diabetes Centre, 220-236 Analby Road, Hull Royal Infirmary, Hull HU3 2JZ, UKAcademic Endocrinology, Diabetes and Metabolism, Hull York Medical School, Michael White Diabetes Centre, 220-236 Analby Road, Hull Royal Infirmary, Hull HU3 2JZ, UKPolycystic ovary syndrome (PCOS) is a common endocrine disorder in women of reproductive age group and is associated with a higher cardiovascular risk. Obesity, mainly visceral adiposity, is prevalent in patients with PCOS. Obesity is associated with low-grade inflammation and raised inflammatory cytokines, both of which are also described in patients with PCOS. In this paper, the potential relationships between fat distribution, adipocyte dysfunction and, altered inflammatory markers in patients with PCOS have been discussed.http://dx.doi.org/10.1155/2010/758656
spellingShingle Thozhukat Sathyapalan
Stephen L. Atkin
Mediators of Inflammation in Polycystic Ovary Syndrome in Relation to Adiposity
Mediators of Inflammation
title Mediators of Inflammation in Polycystic Ovary Syndrome in Relation to Adiposity
title_full Mediators of Inflammation in Polycystic Ovary Syndrome in Relation to Adiposity
title_fullStr Mediators of Inflammation in Polycystic Ovary Syndrome in Relation to Adiposity
title_full_unstemmed Mediators of Inflammation in Polycystic Ovary Syndrome in Relation to Adiposity
title_short Mediators of Inflammation in Polycystic Ovary Syndrome in Relation to Adiposity
title_sort mediators of inflammation in polycystic ovary syndrome in relation to adiposity
url http://dx.doi.org/10.1155/2010/758656
work_keys_str_mv AT thozhukatsathyapalan mediatorsofinflammationinpolycysticovarysyndromeinrelationtoadiposity
AT stephenlatkin mediatorsofinflammationinpolycysticovarysyndromeinrelationtoadiposity