Characteristics of the first immunocompromised patients to receive sipavibart as an early access treatment for COVID-19 pre-exposure prophylaxis in France

France was the first country to grant Sipavibart (AZD3152, an investigational long-acting monoclonal antibody) as a COVID-19 pre-exposure prophylaxis treatment in immunocompromised individuals in December 2023. The first patients to receive Sipavibart had different profiles, but they were all highly...

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Main Authors: Paul Loubet, Benjamin Gaborit, Mathilde Salpin, Hèlene Gardeney, Ilies Benotmane, Thomas Systchenko
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/21645515.2024.2387221
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author Paul Loubet
Benjamin Gaborit
Mathilde Salpin
Hèlene Gardeney
Ilies Benotmane
Thomas Systchenko
author_facet Paul Loubet
Benjamin Gaborit
Mathilde Salpin
Hèlene Gardeney
Ilies Benotmane
Thomas Systchenko
author_sort Paul Loubet
collection DOAJ
description France was the first country to grant Sipavibart (AZD3152, an investigational long-acting monoclonal antibody) as a COVID-19 pre-exposure prophylaxis treatment in immunocompromised individuals in December 2023. The first patients to receive Sipavibart had different profiles, but they were all highly immunocompromised with frequently associated hypogammaglobulinemia and other chronic conditions. No adverse event was reported.
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publishDate 2024-12-01
publisher Taylor & Francis Group
record_format Article
series Human Vaccines & Immunotherapeutics
spelling doaj-art-1e33f7c4698e4801b92f13b3d35ed9e62025-08-20T02:16:50ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2024-12-0120110.1080/21645515.2024.2387221Characteristics of the first immunocompromised patients to receive sipavibart as an early access treatment for COVID-19 pre-exposure prophylaxis in FrancePaul Loubet0Benjamin Gaborit1Mathilde Salpin2Hèlene Gardeney3Ilies Benotmane4Thomas Systchenko5Virulence Bactérienne et Infections Chroniques, University Montpellier, Nîmes, FranceService des Maladies Infectieuses et Tropicales, CHU Nantes, Nantes, FranceService de Pneumologie, AP-HP, Hôpital Bichat, Paris, FranceService d’Hématologie, CHU Poitiers, Poitiers, FranceService de Néphrologie-Dialyse-Transplantation, CHU Strasbourg, Strasbourg, FranceService d’Hématologie, CHU Poitiers, Poitiers, FranceFrance was the first country to grant Sipavibart (AZD3152, an investigational long-acting monoclonal antibody) as a COVID-19 pre-exposure prophylaxis treatment in immunocompromised individuals in December 2023. The first patients to receive Sipavibart had different profiles, but they were all highly immunocompromised with frequently associated hypogammaglobulinemia and other chronic conditions. No adverse event was reported.https://www.tandfonline.com/doi/10.1080/21645515.2024.2387221COVID-19prophylaxisimmunocompromised
spellingShingle Paul Loubet
Benjamin Gaborit
Mathilde Salpin
Hèlene Gardeney
Ilies Benotmane
Thomas Systchenko
Characteristics of the first immunocompromised patients to receive sipavibart as an early access treatment for COVID-19 pre-exposure prophylaxis in France
Human Vaccines & Immunotherapeutics
COVID-19
prophylaxis
immunocompromised
title Characteristics of the first immunocompromised patients to receive sipavibart as an early access treatment for COVID-19 pre-exposure prophylaxis in France
title_full Characteristics of the first immunocompromised patients to receive sipavibart as an early access treatment for COVID-19 pre-exposure prophylaxis in France
title_fullStr Characteristics of the first immunocompromised patients to receive sipavibart as an early access treatment for COVID-19 pre-exposure prophylaxis in France
title_full_unstemmed Characteristics of the first immunocompromised patients to receive sipavibart as an early access treatment for COVID-19 pre-exposure prophylaxis in France
title_short Characteristics of the first immunocompromised patients to receive sipavibart as an early access treatment for COVID-19 pre-exposure prophylaxis in France
title_sort characteristics of the first immunocompromised patients to receive sipavibart as an early access treatment for covid 19 pre exposure prophylaxis in france
topic COVID-19
prophylaxis
immunocompromised
url https://www.tandfonline.com/doi/10.1080/21645515.2024.2387221
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