Preclinical development of a standardized extract of Ilex paraguariensis A.St.-Hil for the treatment of obesity and metabolic syndrome

Preclinical development of a standardized extract of Ilex paraguariensis A.St.-Hil for the treatment of obesity and metabolic syndrome

Obesity is a global epidemic often associated with serious medical complications such as diabetes, hypertension and metabolic dysfunction-associated steatohepatitis. Considering the multifactorial nature of these diseases, medicinal plants could be a valuable therapeutic strategy as their phytoconst...

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Main Authors: Sara E.L. Tolouei, Rodrigo Marcon, Fabiana Cardoso Vilela, Cristina Setim Freitas, Melina Heller, Edineia Lemos de Andrade, Sergio José Macedo Júnior, Adara Áurea dos Santos, Ruth Fernandes Rocha, Guilherme Pasetto Fadanni, Naiani Ferreira Marques, Jarbas Mota Siqueira Júnior, João B. Calixto
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Pharmacological Research
Subjects:
Ilex paraguariensis extract
Obesity
High-fat diet
Type 2 diabetes mellitus
Nonalcoholic steatohepatitis
Metabolic dysfunction
Online Access:http://www.sciencedirect.com/science/article/pii/S1043661825000325
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