Role of Tc-Sulesomab Immunoscintigraphy in the Management of Infection following Deep Brain Stimulation Surgery
Infection constitutes a serious adverse event in patients submitted to deep brain stimulation, often leading to removal of the device. We set to evaluate the potential role of immunoscintigraphy with Tc-labelled antigranulocyte antibody fragments (Tc-sulesomab) in the management of infection followi...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2011-01-01
|
| Series: | Neurology Research International |
| Online Access: | http://dx.doi.org/10.1155/2011/817951 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832558913896054784 |
|---|---|
| author | Raquel Real Paulo Linhares Hélder Fernandes Maria José Rosas Miguel F. Gago Jorge Pereira Rui Vaz |
| author_facet | Raquel Real Paulo Linhares Hélder Fernandes Maria José Rosas Miguel F. Gago Jorge Pereira Rui Vaz |
| author_sort | Raquel Real |
| collection | DOAJ |
| description | Infection constitutes a serious adverse event in patients submitted to deep brain stimulation, often leading to removal of the device. We set to evaluate the potential role of immunoscintigraphy with Tc-labelled antigranulocyte antibody fragments (Tc-sulesomab) in the management of infection following DBS. Tc-sulesomab immunoscintigraphy seems to correlate well with the presence and extent of infection, thus contributing to differentiate between patients who should remove the hardware entirely at presentation and those who could undergo a more conservative approach. Also, Tc-sulesomab immunoscintigraphy has a role in determining the most appropriate timing for reimplantation. Finally, we propose an algorithm for the management of infection following DBS surgery, based on the results of the Tc-sulesomab immunoscintigraphy. |
| format | Article |
| id | doaj-art-1dec9d687e7248d4a7422a48349ed173 |
| institution | Kabale University |
| issn | 2090-1852 2090-1860 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Neurology Research International |
| spelling | doaj-art-1dec9d687e7248d4a7422a48349ed1732025-02-03T01:31:11ZengWileyNeurology Research International2090-18522090-18602011-01-01201110.1155/2011/817951817951Role of Tc-Sulesomab Immunoscintigraphy in the Management of Infection following Deep Brain Stimulation SurgeryRaquel Real0Paulo Linhares1Hélder Fernandes2Maria José Rosas3Miguel F. Gago4Jorge Pereira5Rui Vaz6Department of Neurology, Hospital de São João, Alameda Prof. Hernâni Monteiro, 4200 Porto, PortugalFaculty of Medicine, Universidade do Porto, Alameda Prof. Hernâni Monteiro, 4200 Porto, PortugalDepartment of Nuclear Medicine, Hospital de São João, Alameda Prof. Hernâni Monteiro, 4200 Porto, PortugalDepartment of Neurology, Hospital de São João, Alameda Prof. Hernâni Monteiro, 4200 Porto, PortugalDepartment of Neurology, Hospital de São João, Alameda Prof. Hernâni Monteiro, 4200 Porto, PortugalDepartment of Nuclear Medicine, Hospital de São João, Alameda Prof. Hernâni Monteiro, 4200 Porto, PortugalFaculty of Medicine, Universidade do Porto, Alameda Prof. Hernâni Monteiro, 4200 Porto, PortugalInfection constitutes a serious adverse event in patients submitted to deep brain stimulation, often leading to removal of the device. We set to evaluate the potential role of immunoscintigraphy with Tc-labelled antigranulocyte antibody fragments (Tc-sulesomab) in the management of infection following DBS. Tc-sulesomab immunoscintigraphy seems to correlate well with the presence and extent of infection, thus contributing to differentiate between patients who should remove the hardware entirely at presentation and those who could undergo a more conservative approach. Also, Tc-sulesomab immunoscintigraphy has a role in determining the most appropriate timing for reimplantation. Finally, we propose an algorithm for the management of infection following DBS surgery, based on the results of the Tc-sulesomab immunoscintigraphy.http://dx.doi.org/10.1155/2011/817951 |
| spellingShingle | Raquel Real Paulo Linhares Hélder Fernandes Maria José Rosas Miguel F. Gago Jorge Pereira Rui Vaz Role of Tc-Sulesomab Immunoscintigraphy in the Management of Infection following Deep Brain Stimulation Surgery Neurology Research International |
| title | Role of Tc-Sulesomab Immunoscintigraphy in the Management of Infection following Deep Brain Stimulation Surgery |
| title_full | Role of Tc-Sulesomab Immunoscintigraphy in the Management of Infection following Deep Brain Stimulation Surgery |
| title_fullStr | Role of Tc-Sulesomab Immunoscintigraphy in the Management of Infection following Deep Brain Stimulation Surgery |
| title_full_unstemmed | Role of Tc-Sulesomab Immunoscintigraphy in the Management of Infection following Deep Brain Stimulation Surgery |
| title_short | Role of Tc-Sulesomab Immunoscintigraphy in the Management of Infection following Deep Brain Stimulation Surgery |
| title_sort | role of tc sulesomab immunoscintigraphy in the management of infection following deep brain stimulation surgery |
| url | http://dx.doi.org/10.1155/2011/817951 |
| work_keys_str_mv | AT raquelreal roleoftcsulesomabimmunoscintigraphyinthemanagementofinfectionfollowingdeepbrainstimulationsurgery AT paulolinhares roleoftcsulesomabimmunoscintigraphyinthemanagementofinfectionfollowingdeepbrainstimulationsurgery AT helderfernandes roleoftcsulesomabimmunoscintigraphyinthemanagementofinfectionfollowingdeepbrainstimulationsurgery AT mariajoserosas roleoftcsulesomabimmunoscintigraphyinthemanagementofinfectionfollowingdeepbrainstimulationsurgery AT miguelfgago roleoftcsulesomabimmunoscintigraphyinthemanagementofinfectionfollowingdeepbrainstimulationsurgery AT jorgepereira roleoftcsulesomabimmunoscintigraphyinthemanagementofinfectionfollowingdeepbrainstimulationsurgery AT ruivaz roleoftcsulesomabimmunoscintigraphyinthemanagementofinfectionfollowingdeepbrainstimulationsurgery |