Demographics and regional trends of ischemic heart disease-related mortality in older adults in the United States, 1999-2020.
<h4>Background</h4>Ischemic heart disease (IHD) has a significant impact on public health and healthcare expenditures in the United States (US).<h4>Methods</h4>We used data from the CDC WONDER database from 1999-2020 to identify trends in the IHD-related mortality of patients...
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Public Library of Science (PLoS)
2025-01-01
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| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0318073&type=printable |
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| author | Fakhar Latif Muhammad Moiz Nasir Wajeeh Ur Rehman Mohammed Hamza Jishanth Mattumpuram Komail Khalid Meer Helme Silvet Alon Yarkoni Mouhamed Amr Sabouni Nabil Braiteh Keyoor Patel Abdulqadir J Nashwan |
| author_facet | Fakhar Latif Muhammad Moiz Nasir Wajeeh Ur Rehman Mohammed Hamza Jishanth Mattumpuram Komail Khalid Meer Helme Silvet Alon Yarkoni Mouhamed Amr Sabouni Nabil Braiteh Keyoor Patel Abdulqadir J Nashwan |
| author_sort | Fakhar Latif |
| collection | DOAJ |
| description | <h4>Background</h4>Ischemic heart disease (IHD) has a significant impact on public health and healthcare expenditures in the United States (US).<h4>Methods</h4>We used data from the CDC WONDER database from 1999-2020 to identify trends in the IHD-related mortality of patients ≥ 75 years in the US. AAMRs per 100,000 population and APC were calculated and categorized by year, sex, race, and geographic divisions.<h4>Results</h4>Between 1999 and 2020, a total of 8,124,568 IHD-related deaths were recorded. Notable declines in AAMR were observed from 1999 to 2014 (APC: -3.86) and from 2014 to 2018 (APC: -2.55), with an overall increase from 2018 to 2020 (APC: 3.76). Older men consistently demonstrated higher AAMRs than older females, with AAMRs for both sexes decreasing steadily from 1999 to 2018 and increasing in 2020. When stratified by race/ethnicity, Whites (1931.7) had the highest AAMR, followed by Blacks (1836.5), American Indians (1510.5), Hispanics (1464.4), and Asians (1093.6). Furthermore, nonmetropolitan areas (2015.2) showed greater AAMRs than metropolitan areas (1841.8). The ≥ 85-year group consistently exhibited higher IHD-related mortality rates compared to the 75-84 years group. In comparison, the older group [≥75 years] (1873.0) consistently exhibited higher IHD-related AAMRs than the younger group [<75 years] (64.0) throughout the study, showing a significant disparity. Chronic IHD (1552.0) consistently showed the highest AAMRs throughout the study, surpassing myocardial infarction (515.6), other ischemic heart diseases (24.0), and angina pectoris (5.6).<h4>Conclusion</h4>Targeted interventions and resource allocation are crucial for areas with high IHD-related mortality. Public health policies should address demographic and geographical disparities, with further research for effective strategies. |
| format | Article |
| id | doaj-art-1de91f1d06bd47c5a65e8899fe2a2eb4 |
| institution | Kabale University |
| issn | 1932-6203 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Public Library of Science (PLoS) |
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| series | PLoS ONE |
| spelling | doaj-art-1de91f1d06bd47c5a65e8899fe2a2eb42025-02-05T05:32:09ZengPublic Library of Science (PLoS)PLoS ONE1932-62032025-01-01201e031807310.1371/journal.pone.0318073Demographics and regional trends of ischemic heart disease-related mortality in older adults in the United States, 1999-2020.Fakhar LatifMuhammad Moiz NasirWajeeh Ur RehmanMohammed HamzaJishanth MattumpuramKomail Khalid MeerHelme SilvetAlon YarkoniMouhamed Amr SabouniNabil BraitehKeyoor PatelAbdulqadir J Nashwan<h4>Background</h4>Ischemic heart disease (IHD) has a significant impact on public health and healthcare expenditures in the United States (US).<h4>Methods</h4>We used data from the CDC WONDER database from 1999-2020 to identify trends in the IHD-related mortality of patients ≥ 75 years in the US. AAMRs per 100,000 population and APC were calculated and categorized by year, sex, race, and geographic divisions.<h4>Results</h4>Between 1999 and 2020, a total of 8,124,568 IHD-related deaths were recorded. Notable declines in AAMR were observed from 1999 to 2014 (APC: -3.86) and from 2014 to 2018 (APC: -2.55), with an overall increase from 2018 to 2020 (APC: 3.76). Older men consistently demonstrated higher AAMRs than older females, with AAMRs for both sexes decreasing steadily from 1999 to 2018 and increasing in 2020. When stratified by race/ethnicity, Whites (1931.7) had the highest AAMR, followed by Blacks (1836.5), American Indians (1510.5), Hispanics (1464.4), and Asians (1093.6). Furthermore, nonmetropolitan areas (2015.2) showed greater AAMRs than metropolitan areas (1841.8). The ≥ 85-year group consistently exhibited higher IHD-related mortality rates compared to the 75-84 years group. In comparison, the older group [≥75 years] (1873.0) consistently exhibited higher IHD-related AAMRs than the younger group [<75 years] (64.0) throughout the study, showing a significant disparity. Chronic IHD (1552.0) consistently showed the highest AAMRs throughout the study, surpassing myocardial infarction (515.6), other ischemic heart diseases (24.0), and angina pectoris (5.6).<h4>Conclusion</h4>Targeted interventions and resource allocation are crucial for areas with high IHD-related mortality. Public health policies should address demographic and geographical disparities, with further research for effective strategies.https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0318073&type=printable |
| spellingShingle | Fakhar Latif Muhammad Moiz Nasir Wajeeh Ur Rehman Mohammed Hamza Jishanth Mattumpuram Komail Khalid Meer Helme Silvet Alon Yarkoni Mouhamed Amr Sabouni Nabil Braiteh Keyoor Patel Abdulqadir J Nashwan Demographics and regional trends of ischemic heart disease-related mortality in older adults in the United States, 1999-2020. PLoS ONE |
| title | Demographics and regional trends of ischemic heart disease-related mortality in older adults in the United States, 1999-2020. |
| title_full | Demographics and regional trends of ischemic heart disease-related mortality in older adults in the United States, 1999-2020. |
| title_fullStr | Demographics and regional trends of ischemic heart disease-related mortality in older adults in the United States, 1999-2020. |
| title_full_unstemmed | Demographics and regional trends of ischemic heart disease-related mortality in older adults in the United States, 1999-2020. |
| title_short | Demographics and regional trends of ischemic heart disease-related mortality in older adults in the United States, 1999-2020. |
| title_sort | demographics and regional trends of ischemic heart disease related mortality in older adults in the united states 1999 2020 |
| url | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0318073&type=printable |
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