PDK1/mTOR Signaling in Myeloid Cells Differentially Regulates the Early and Late Stages of Sepsis

The cecal ligation and perforation (CLP) model is the gold standard for the polymicrobial sepsis. In the CLP mice, the myeloid cells play an important role in septic shock. The phenotypes and the activation state of the macrophage and neutrophil correlate with their metabolism. In the present study,...

Full description

Saved in:
Bibliographic Details
Main Authors: Juan Du, Guoli Li, Mingxi Hua, Junyan Han, Yu Hao, Hui Zeng, Ang Li, Yaxian Kong
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2020/5437175
Tags: Add Tag
No Tags, Be the first to tag this record!