Isolation and identification of patient-derived liver cancer stem cells and development of personalized treatment strategies

Isolation and identification of patient-derived liver cancer stem cells and development of personalized treatment strategies

Abstract Background Liver cancer stem cells (LCSCs) are thought to drive the metastasis and recurrence, however, the heterogeneity of molecular markers of LCSCs has hindered the development of effective methods to isolate them. Methods This study introduced an effective approach to isolate and cultu...

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Main Authors: Tingting Guo, Shuai Zhang, Weiping Zeng, Yan Liang, Jinghe Xie, ShouPei Liu, Yaqi Qiu, Yingjie Fu, Yimeng Ou, Keqiang Ma, Bailin Wang, Weili Gu, Yuyou Duan
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Journal of Translational Medicine
Subjects:
Liver cancer
Cancer stem cells
Personalized therapy
Isolation and culture
Online Access:https://doi.org/10.1186/s12967-024-05870-9
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