Contribution of ROS and metabolic status to neonatal and adult CD8+ T cell activation.

Contribution of ROS and metabolic status to neonatal and adult CD8+ T cell activation.

In neonatal T cells, a low response to infection contributes to a high incidence of morbidity and mortality of neonates. Here we have evaluated the impact of the cytoplasmic and mitochondrial levels of Reactive Oxygen Species of adult and neonatal CD8+ T cells on their activation potential. We have...

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Main Authors: José Antonio Sánchez-Villanueva, Otoniel Rodríguez-Jorge, Oscar Ramírez-Pliego, Gabriela Rosas Salgado, Wassim Abou-Jaoudé, Céline Hernandez, Aurélien Naldi, Denis Thieffry, María Angélica Santana
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0226388&type=printable
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