Minimal Clinically Important Difference of Average Daily Steps Measured Through a Consumer Smartwatch in People With Mild-to-Moderate Parkinson Disease: Cross-Sectional Study
Abstract BackgroundRecent studies demonstrated the validity, reliability, and accuracy of consumer smartwatches for measuring daily steps in people with Parkinson disease (PD). However, no study to date has estimated the minimal clinically important difference (MCID) for avera...
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| Format: | Article |
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JMIR Publications
2025-07-01
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| Series: | JMIR mHealth and uHealth |
| Online Access: | https://mhealth.jmir.org/2025/1/e64213 |
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| author | Edoardo Bianchini Marika Alborghetti Silvia Galli Clint Hansen Alessandro Zampogna Antonio Suppa Marco Salvetti Francesco Ernesto Pontieri Domiziana Rinaldi Nicolas Vuillerme |
| author_facet | Edoardo Bianchini Marika Alborghetti Silvia Galli Clint Hansen Alessandro Zampogna Antonio Suppa Marco Salvetti Francesco Ernesto Pontieri Domiziana Rinaldi Nicolas Vuillerme |
| author_sort | Edoardo Bianchini |
| collection | DOAJ |
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Abstract
BackgroundRecent studies demonstrated the validity, reliability, and accuracy of consumer smartwatches for measuring daily steps in people with Parkinson disease (PD). However, no study to date has estimated the minimal clinically important difference (MCID) for average daily steps (avDS), measured through a consumer smartwatch in people with PD.
ObjectiveThis study aimed to calculate the MCID of avDS, measured through a commercial smartwatch (Garmin Vivosmart 4) in people with PD.
MethodsPeople with PD with a disease stage <4, without cognitive impairment, and who were able to walk unaided, wore a Garmin Vivosmart 4 smartwatch for 5 consecutive days on the wrist least affected by the disease, allowing the computation of avDS. To define the 3 levels of MCID for avDS, we used an anchor-based method linked to: (1) scales capturing subtle changes in global mobility and motor functions, (2) clinical and health-related measures, and (3) disease-related patient-reported outcomes. Linear regressions, Student t
ResultsA total of 100 people with PD were enrolled. Participants took on average 5949 (SD 3034) daily steps, ranging from 357 to 12,620. The MCID of avDS anchored to standardized measures of motor symptoms and mobility was 581 steps/day (range 554‐608) or around 10% of mean avDS in our population. The MCID of avDS anchored to clinical and health-related variables was 1200 steps/day (range 350‐1683), or around 20% of mean avDS in our population. Finally, the MCID of avDS anchored to disease-related patient-reported outcomes was 1592 steps/day (range 594‐2589), or around 27% of the mean avDS in our population.
ConclusionsThese findings could be relevant for designing future clinical trials involving avDS as a digital mobility outcome in daily life for people with PD and evaluating the effectiveness of the intervention promoting free-living walking in this population. |
| format | Article |
| id | doaj-art-1dbf6c2ca5a0431e8d81f9d3eaa60b8d |
| institution | Kabale University |
| issn | 2291-5222 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | JMIR Publications |
| record_format | Article |
| series | JMIR mHealth and uHealth |
| spelling | doaj-art-1dbf6c2ca5a0431e8d81f9d3eaa60b8d2025-08-20T04:00:54ZengJMIR PublicationsJMIR mHealth and uHealth2291-52222025-07-0113e64213e6421310.2196/64213Minimal Clinically Important Difference of Average Daily Steps Measured Through a Consumer Smartwatch in People With Mild-to-Moderate Parkinson Disease: Cross-Sectional StudyEdoardo Bianchinihttp://orcid.org/0000-0001-7955-3369Marika Alborghettihttp://orcid.org/0000-0001-9327-6660Silvia Gallihttp://orcid.org/0009-0004-2036-4650Clint Hansenhttp://orcid.org/0000-0003-4813-3868Alessandro Zampognahttp://orcid.org/0000-0002-0227-1993Antonio Suppahttp://orcid.org/0000-0001-9903-5550Marco Salvettihttp://orcid.org/0000-0002-0501-8803Francesco Ernesto Pontierihttp://orcid.org/0000-0002-8693-8432Domiziana Rinaldihttp://orcid.org/0000-0002-8011-087XNicolas Vuillermehttp://orcid.org/0000-0003-3773-393X Abstract BackgroundRecent studies demonstrated the validity, reliability, and accuracy of consumer smartwatches for measuring daily steps in people with Parkinson disease (PD). However, no study to date has estimated the minimal clinically important difference (MCID) for average daily steps (avDS), measured through a consumer smartwatch in people with PD. ObjectiveThis study aimed to calculate the MCID of avDS, measured through a commercial smartwatch (Garmin Vivosmart 4) in people with PD. MethodsPeople with PD with a disease stage <4, without cognitive impairment, and who were able to walk unaided, wore a Garmin Vivosmart 4 smartwatch for 5 consecutive days on the wrist least affected by the disease, allowing the computation of avDS. To define the 3 levels of MCID for avDS, we used an anchor-based method linked to: (1) scales capturing subtle changes in global mobility and motor functions, (2) clinical and health-related measures, and (3) disease-related patient-reported outcomes. Linear regressions, Student t ResultsA total of 100 people with PD were enrolled. Participants took on average 5949 (SD 3034) daily steps, ranging from 357 to 12,620. The MCID of avDS anchored to standardized measures of motor symptoms and mobility was 581 steps/day (range 554‐608) or around 10% of mean avDS in our population. The MCID of avDS anchored to clinical and health-related variables was 1200 steps/day (range 350‐1683), or around 20% of mean avDS in our population. Finally, the MCID of avDS anchored to disease-related patient-reported outcomes was 1592 steps/day (range 594‐2589), or around 27% of the mean avDS in our population. ConclusionsThese findings could be relevant for designing future clinical trials involving avDS as a digital mobility outcome in daily life for people with PD and evaluating the effectiveness of the intervention promoting free-living walking in this population.https://mhealth.jmir.org/2025/1/e64213 |
| spellingShingle | Edoardo Bianchini Marika Alborghetti Silvia Galli Clint Hansen Alessandro Zampogna Antonio Suppa Marco Salvetti Francesco Ernesto Pontieri Domiziana Rinaldi Nicolas Vuillerme Minimal Clinically Important Difference of Average Daily Steps Measured Through a Consumer Smartwatch in People With Mild-to-Moderate Parkinson Disease: Cross-Sectional Study JMIR mHealth and uHealth |
| title | Minimal Clinically Important Difference of Average Daily Steps Measured Through a Consumer Smartwatch in People With Mild-to-Moderate Parkinson Disease: Cross-Sectional Study |
| title_full | Minimal Clinically Important Difference of Average Daily Steps Measured Through a Consumer Smartwatch in People With Mild-to-Moderate Parkinson Disease: Cross-Sectional Study |
| title_fullStr | Minimal Clinically Important Difference of Average Daily Steps Measured Through a Consumer Smartwatch in People With Mild-to-Moderate Parkinson Disease: Cross-Sectional Study |
| title_full_unstemmed | Minimal Clinically Important Difference of Average Daily Steps Measured Through a Consumer Smartwatch in People With Mild-to-Moderate Parkinson Disease: Cross-Sectional Study |
| title_short | Minimal Clinically Important Difference of Average Daily Steps Measured Through a Consumer Smartwatch in People With Mild-to-Moderate Parkinson Disease: Cross-Sectional Study |
| title_sort | minimal clinically important difference of average daily steps measured through a consumer smartwatch in people with mild to moderate parkinson disease cross sectional study |
| url | https://mhealth.jmir.org/2025/1/e64213 |
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