Acute Acalculous Cholecystitis: A Rare Presentation of Primary Epstein-Barr Virus Infection in Adults—Case Report and Review of the Literature
Primary Epstein-Barr virus (EBV) infection is almost always a self-limited disease characterized by sore throat, fever, and lymphadenopathy. Hepatic involvement is usually characterized by mild elevations of aminotransferases and resolves spontaneously. Although isolated gallbladder wall thickness h...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2017-01-01
|
| Series: | Case Reports in Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/2017/5790102 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832566882357477376 |
|---|---|
| author | Zuhal Yesilbag Asli Karadeniz Fatih Oner Kaya |
| author_facet | Zuhal Yesilbag Asli Karadeniz Fatih Oner Kaya |
| author_sort | Zuhal Yesilbag |
| collection | DOAJ |
| description | Primary Epstein-Barr virus (EBV) infection is almost always a self-limited disease characterized by sore throat, fever, and lymphadenopathy. Hepatic involvement is usually characterized by mild elevations of aminotransferases and resolves spontaneously. Although isolated gallbladder wall thickness has been reported in these patients, acute acalculous cholecystitis is an atypical presentation of primary EBV infection. We presented a young women admitted with a 10-day history of fever, nausea, malaise who had jaundice and right upper quadrant tenderness on the physical examination. Based on diagnostic laboratory tests and abdominal ultrasonographic findings, cholestasis and acute acalculous cholecystitis were diagnosed. Serology performed for EBV revealed the acute EBV infection. Symptoms and clinical course gradually improved with the conservative therapy, and at the 1-month follow-up laboratory findings were normal. We reviewed 16 adult cases with EBV-associated AAC in the literature. Classic symptoms of EBV infection were not predominant and all cases experienced gastrointestinal symptoms. Only one patient underwent surgery and all other patients recovered with conservative therapy. The development of AAC should be kept in mind in patients with cholestatic hepatitis due to EBV infection to avoid unnecessary surgical therapy and overuse of antibiotics. |
| format | Article |
| id | doaj-art-1db8693d57ad479d9b29b2919d18ec12 |
| institution | Kabale University |
| issn | 2090-6625 2090-6633 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Infectious Diseases |
| spelling | doaj-art-1db8693d57ad479d9b29b2919d18ec122025-02-03T01:02:55ZengWileyCase Reports in Infectious Diseases2090-66252090-66332017-01-01201710.1155/2017/57901025790102Acute Acalculous Cholecystitis: A Rare Presentation of Primary Epstein-Barr Virus Infection in Adults—Case Report and Review of the LiteratureZuhal Yesilbag0Asli Karadeniz1Fatih Oner Kaya2Department of Infectious Diseases and Clinical Microbiology, Bakirkoy Dr. Sadi Konuk Education and Research Hospital, Istanbul, TurkeyDepartment of Infectious Diseases and Clinical Microbiology, Maltepe University Faculty of Medicine, Istanbul, TurkeyDepartment of Internal Medicine, Maltepe University Faculty of Medicine, Istanbul, TurkeyPrimary Epstein-Barr virus (EBV) infection is almost always a self-limited disease characterized by sore throat, fever, and lymphadenopathy. Hepatic involvement is usually characterized by mild elevations of aminotransferases and resolves spontaneously. Although isolated gallbladder wall thickness has been reported in these patients, acute acalculous cholecystitis is an atypical presentation of primary EBV infection. We presented a young women admitted with a 10-day history of fever, nausea, malaise who had jaundice and right upper quadrant tenderness on the physical examination. Based on diagnostic laboratory tests and abdominal ultrasonographic findings, cholestasis and acute acalculous cholecystitis were diagnosed. Serology performed for EBV revealed the acute EBV infection. Symptoms and clinical course gradually improved with the conservative therapy, and at the 1-month follow-up laboratory findings were normal. We reviewed 16 adult cases with EBV-associated AAC in the literature. Classic symptoms of EBV infection were not predominant and all cases experienced gastrointestinal symptoms. Only one patient underwent surgery and all other patients recovered with conservative therapy. The development of AAC should be kept in mind in patients with cholestatic hepatitis due to EBV infection to avoid unnecessary surgical therapy and overuse of antibiotics.http://dx.doi.org/10.1155/2017/5790102 |
| spellingShingle | Zuhal Yesilbag Asli Karadeniz Fatih Oner Kaya Acute Acalculous Cholecystitis: A Rare Presentation of Primary Epstein-Barr Virus Infection in Adults—Case Report and Review of the Literature Case Reports in Infectious Diseases |
| title | Acute Acalculous Cholecystitis: A Rare Presentation of Primary Epstein-Barr Virus Infection in Adults—Case Report and Review of the Literature |
| title_full | Acute Acalculous Cholecystitis: A Rare Presentation of Primary Epstein-Barr Virus Infection in Adults—Case Report and Review of the Literature |
| title_fullStr | Acute Acalculous Cholecystitis: A Rare Presentation of Primary Epstein-Barr Virus Infection in Adults—Case Report and Review of the Literature |
| title_full_unstemmed | Acute Acalculous Cholecystitis: A Rare Presentation of Primary Epstein-Barr Virus Infection in Adults—Case Report and Review of the Literature |
| title_short | Acute Acalculous Cholecystitis: A Rare Presentation of Primary Epstein-Barr Virus Infection in Adults—Case Report and Review of the Literature |
| title_sort | acute acalculous cholecystitis a rare presentation of primary epstein barr virus infection in adults case report and review of the literature |
| url | http://dx.doi.org/10.1155/2017/5790102 |
| work_keys_str_mv | AT zuhalyesilbag acuteacalculouscholecystitisararepresentationofprimaryepsteinbarrvirusinfectioninadultscasereportandreviewoftheliterature AT aslikaradeniz acuteacalculouscholecystitisararepresentationofprimaryepsteinbarrvirusinfectioninadultscasereportandreviewoftheliterature AT fatihonerkaya acuteacalculouscholecystitisararepresentationofprimaryepsteinbarrvirusinfectioninadultscasereportandreviewoftheliterature |