A Case of Eosinophilic Granulomatosis with Polyangiitis Complicated with A IgG4 Related Disease Like Symptoms

We report a case of eosinophilic granulomatosis with polyangiitis (EGPA) complicated with a IgG4 related disease like symptoms presenting as eyelid swellings. In the present case, the serum level of IgG4 and the ratio of IgG4 to IgG were generally increased by the disease course of EGPA. Considering...

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Main Authors: Suguru Sato, Julia Morimoto, Yasuharu Oguchi, Takashi Umeda, Takaya Kawamata, Mami Rikimaru, Tatsuhiko Koizumi, Ryuichi Togawa, Yasuhito Suzuki, Yuki Sato, Manabu Uematsu, Hiroyuki Minemura, Takefumi Nikaido, Atsuro Fukuhara, Junpei Saito, Kenya Kanazawa, Yoshinori Tanino, Mitsuru Munakata, Yoko Shibata
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Case Reports in Immunology
Online Access:http://dx.doi.org/10.1155/2018/3763084
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author Suguru Sato
Julia Morimoto
Yasuharu Oguchi
Takashi Umeda
Takaya Kawamata
Mami Rikimaru
Tatsuhiko Koizumi
Ryuichi Togawa
Yasuhito Suzuki
Yuki Sato
Manabu Uematsu
Hiroyuki Minemura
Takefumi Nikaido
Atsuro Fukuhara
Junpei Saito
Kenya Kanazawa
Yoshinori Tanino
Mitsuru Munakata
Yoko Shibata
author_facet Suguru Sato
Julia Morimoto
Yasuharu Oguchi
Takashi Umeda
Takaya Kawamata
Mami Rikimaru
Tatsuhiko Koizumi
Ryuichi Togawa
Yasuhito Suzuki
Yuki Sato
Manabu Uematsu
Hiroyuki Minemura
Takefumi Nikaido
Atsuro Fukuhara
Junpei Saito
Kenya Kanazawa
Yoshinori Tanino
Mitsuru Munakata
Yoko Shibata
author_sort Suguru Sato
collection DOAJ
description We report a case of eosinophilic granulomatosis with polyangiitis (EGPA) complicated with a IgG4 related disease like symptoms presenting as eyelid swellings. In the present case, the serum level of IgG4 and the ratio of IgG4 to IgG were generally increased by the disease course of EGPA. Considering the course of clinical symptoms, there is a possibility that orbital manifestations were one of the clinical features during the disease course of EGPA while the histological features of right eyelid tissue and other ocular manifestations were consistent with the diagnosis of IgG4 related disease.
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publishDate 2018-01-01
publisher Wiley
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series Case Reports in Immunology
spelling doaj-art-1db6e8b2fcff4770bd12428573f3db802025-02-03T01:23:59ZengWileyCase Reports in Immunology2090-66092090-66172018-01-01201810.1155/2018/37630843763084A Case of Eosinophilic Granulomatosis with Polyangiitis Complicated with A IgG4 Related Disease Like SymptomsSuguru Sato0Julia Morimoto1Yasuharu Oguchi2Takashi Umeda3Takaya Kawamata4Mami Rikimaru5Tatsuhiko Koizumi6Ryuichi Togawa7Yasuhito Suzuki8Yuki Sato9Manabu Uematsu10Hiroyuki Minemura11Takefumi Nikaido12Atsuro Fukuhara13Junpei Saito14Kenya Kanazawa15Yoshinori Tanino16Mitsuru Munakata17Yoko Shibata18Department of Pulmonary Medicine, School of Medicine, Fukushima Medical University, Fukushima, JapanDepartment of Pulmonary Medicine, School of Medicine, Fukushima Medical University, Fukushima, JapanDepartment of Ophthalmology, School of Medicine, Fukushima Medical University, Fukushima, JapanDepartment of Pulmonary Medicine, School of Medicine, Fukushima Medical University, Fukushima, JapanDepartment of Pulmonary Medicine, School of Medicine, Fukushima Medical University, Fukushima, JapanDepartment of Pulmonary Medicine, School of Medicine, Fukushima Medical University, Fukushima, JapanDepartment of Pulmonary Medicine, School of Medicine, Fukushima Medical University, Fukushima, JapanDepartment of Pulmonary Medicine, School of Medicine, Fukushima Medical University, Fukushima, JapanDepartment of Pulmonary Medicine, School of Medicine, Fukushima Medical University, Fukushima, JapanDepartment of Pulmonary Medicine, School of Medicine, Fukushima Medical University, Fukushima, JapanDepartment of Pulmonary Medicine, School of Medicine, Fukushima Medical University, Fukushima, JapanDepartment of Pulmonary Medicine, School of Medicine, Fukushima Medical University, Fukushima, JapanDepartment of Pulmonary Medicine, School of Medicine, Fukushima Medical University, Fukushima, JapanDepartment of Pulmonary Medicine, School of Medicine, Fukushima Medical University, Fukushima, JapanDepartment of Pulmonary Medicine, School of Medicine, Fukushima Medical University, Fukushima, JapanDepartment of Pulmonary Medicine, School of Medicine, Fukushima Medical University, Fukushima, JapanDepartment of Pulmonary Medicine, School of Medicine, Fukushima Medical University, Fukushima, JapanDepartment of Infectious Disease and Pulmonary Medicine, Aizu Medical Center, Fukushima Medical University, Aizuwakamatsu, JapanDepartment of Pulmonary Medicine, School of Medicine, Fukushima Medical University, Fukushima, JapanWe report a case of eosinophilic granulomatosis with polyangiitis (EGPA) complicated with a IgG4 related disease like symptoms presenting as eyelid swellings. In the present case, the serum level of IgG4 and the ratio of IgG4 to IgG were generally increased by the disease course of EGPA. Considering the course of clinical symptoms, there is a possibility that orbital manifestations were one of the clinical features during the disease course of EGPA while the histological features of right eyelid tissue and other ocular manifestations were consistent with the diagnosis of IgG4 related disease.http://dx.doi.org/10.1155/2018/3763084
spellingShingle Suguru Sato
Julia Morimoto
Yasuharu Oguchi
Takashi Umeda
Takaya Kawamata
Mami Rikimaru
Tatsuhiko Koizumi
Ryuichi Togawa
Yasuhito Suzuki
Yuki Sato
Manabu Uematsu
Hiroyuki Minemura
Takefumi Nikaido
Atsuro Fukuhara
Junpei Saito
Kenya Kanazawa
Yoshinori Tanino
Mitsuru Munakata
Yoko Shibata
A Case of Eosinophilic Granulomatosis with Polyangiitis Complicated with A IgG4 Related Disease Like Symptoms
Case Reports in Immunology
title A Case of Eosinophilic Granulomatosis with Polyangiitis Complicated with A IgG4 Related Disease Like Symptoms
title_full A Case of Eosinophilic Granulomatosis with Polyangiitis Complicated with A IgG4 Related Disease Like Symptoms
title_fullStr A Case of Eosinophilic Granulomatosis with Polyangiitis Complicated with A IgG4 Related Disease Like Symptoms
title_full_unstemmed A Case of Eosinophilic Granulomatosis with Polyangiitis Complicated with A IgG4 Related Disease Like Symptoms
title_short A Case of Eosinophilic Granulomatosis with Polyangiitis Complicated with A IgG4 Related Disease Like Symptoms
title_sort case of eosinophilic granulomatosis with polyangiitis complicated with a igg4 related disease like symptoms
url http://dx.doi.org/10.1155/2018/3763084
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