Electroacupuncture and Tongbian decoction ameliorate CUMS-induced depression and constipation in mice via TPH2/5-HT pathway of the gut-brain axis

Electroacupuncture and Tongbian decoction ameliorate CUMS-induced depression and constipation in mice via TPH2/5-HT pathway of the gut-brain axis

Depression is commonly associated with gastrointestinal (GI) disorders, such as constipation, which can potentially intensify depressive symptoms. The interplay between these conditions is believed to be facilitated by the gut-brain axis, which suggests a complex bidirectional interaction. Current t...

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Bibliographic Details
Main Authors: Yi Chen, Peihua Shen, Qi Li, Shun Seng Ong, Yunzhi Qian, Hai Lu, Ming Li, Tianshu Xu
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Brain Research Bulletin
Subjects:
Electroacupuncture
Tongbian decoction
CUMS
Constipation
TPH2
5-HT
Online Access:http://www.sciencedirect.com/science/article/pii/S036192302500019X
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