Epidemiological, clinical and imaging profile of Multiple Sclerosis

<p><strong>Background:</strong> multiple sclerosis is a neurological, autoimmune, degenerative, chronic and progressive demyelinating disease associated with different genetic and environmental factors.<br /><strong>Objective:</strong> to characterize epidemiologi...

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Main Authors: Làzaro Aurelio Vàzquez Gòmez, Carlos Hidalgo Mesa, Benita Mabel Beltrán González, Yunier Broche Pérez, Ana María Mederos Herrera
Format: Article
Language:Spanish
Published: Centro Provincial de Información de Ciencias Médicas. Cienfuegos 2021-12-01
Series:Medisur
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Online Access:http://medisur.sld.cu/index.php/medisur/article/view/5254
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author Làzaro Aurelio Vàzquez Gòmez
Carlos Hidalgo Mesa
Benita Mabel Beltrán González
Yunier Broche Pérez
Ana María Mederos Herrera
author_facet Làzaro Aurelio Vàzquez Gòmez
Carlos Hidalgo Mesa
Benita Mabel Beltrán González
Yunier Broche Pérez
Ana María Mederos Herrera
author_sort Làzaro Aurelio Vàzquez Gòmez
collection DOAJ
description <p><strong>Background:</strong> multiple sclerosis is a neurological, autoimmune, degenerative, chronic and progressive demyelinating disease associated with different genetic and environmental factors.<br /><strong>Objective:</strong> to characterize epidemiologically, clinically and imaging patients with a diagnosis of multiple sclerosis.<br /><strong>Methods:</strong> observational, descriptive, cross-sectional study on all patients with a diagnosis of multiple sclerosis with follow-up at the Arnaldo Milián Castro Provincial University Clinical-Surgical Hospital, in Villa Clara during the period from January 2014 to December 2019. The epidemiological variables analyzed: sex, age of disease onset, skin color, place of origin; clinical variables: symptoms at the beginning and at present; number of shoots; years of evolution, clinical forms; Imaging variables: number of lesions, location, atrophy or change in signal intensity of the corpus callosum and McDonald's criterion fulfilled.<br /><strong>Results:</strong> there was a higher incidence of females with 80 patients. It was found that 59 patients had a relapsing-remitting clinical form, 21 patients had a secondary progressive form, 4 patients had a primary progressive and 2 patients had a relapsing progressive one. Symptoms: motor deficit, sensory deficit and cerebellar alterations were the most frequent at the beginning and at present. Disability evaluated as minimal was found in 50 patients and 31 patients had 2 to 4 lesions on nuclear magnetic resonance.<br /><strong>Conclusions:</strong> Adequate epidemiological information on patients with multiple sclerosis in Villa Clara was obtained satisfactorily. It is important to consider this report as a basis for decision-making on issues of projection of treatment and care, aspects of great importance in high-cost diseases, such as multiple sclerosis.</p>
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spelling doaj-art-1d2e68b4630b43bbb660c2c736ec4e972025-01-30T21:28:58ZspaCentro Provincial de Información de Ciencias Médicas. CienfuegosMedisur1727-897X2021-12-011969489582067Epidemiological, clinical and imaging profile of Multiple SclerosisLàzaro Aurelio Vàzquez Gòmez0Carlos Hidalgo Mesa1Benita Mabel Beltrán González2Yunier Broche Pérez3Ana María Mederos Herrera4Universidad de Ciencias Médicas de Villa Clara. Cuba. Hospital Provincial Clínico-Quirúrgico Universitario Arnaldo Milián Castro. Villa Clara. Cuba.Hospital Militar Clínico-Quirúrgico Universitario Manuel Piti Fajardo. Villa Clara. Cuba.Universidad de Ciencias Médicas de Villa Clara. Cuba.Universidad Central Martha Abreu de las Villas. Cuba.Hospital Universitario Pediátrico José Luis Miranda. Villa Clara. Cuba.<p><strong>Background:</strong> multiple sclerosis is a neurological, autoimmune, degenerative, chronic and progressive demyelinating disease associated with different genetic and environmental factors.<br /><strong>Objective:</strong> to characterize epidemiologically, clinically and imaging patients with a diagnosis of multiple sclerosis.<br /><strong>Methods:</strong> observational, descriptive, cross-sectional study on all patients with a diagnosis of multiple sclerosis with follow-up at the Arnaldo Milián Castro Provincial University Clinical-Surgical Hospital, in Villa Clara during the period from January 2014 to December 2019. The epidemiological variables analyzed: sex, age of disease onset, skin color, place of origin; clinical variables: symptoms at the beginning and at present; number of shoots; years of evolution, clinical forms; Imaging variables: number of lesions, location, atrophy or change in signal intensity of the corpus callosum and McDonald's criterion fulfilled.<br /><strong>Results:</strong> there was a higher incidence of females with 80 patients. It was found that 59 patients had a relapsing-remitting clinical form, 21 patients had a secondary progressive form, 4 patients had a primary progressive and 2 patients had a relapsing progressive one. Symptoms: motor deficit, sensory deficit and cerebellar alterations were the most frequent at the beginning and at present. Disability evaluated as minimal was found in 50 patients and 31 patients had 2 to 4 lesions on nuclear magnetic resonance.<br /><strong>Conclusions:</strong> Adequate epidemiological information on patients with multiple sclerosis in Villa Clara was obtained satisfactorily. It is important to consider this report as a basis for decision-making on issues of projection of treatment and care, aspects of great importance in high-cost diseases, such as multiple sclerosis.</p>http://medisur.sld.cu/index.php/medisur/article/view/5254esclerosis múltipleepidemiologíaestudio observacional
spellingShingle Làzaro Aurelio Vàzquez Gòmez
Carlos Hidalgo Mesa
Benita Mabel Beltrán González
Yunier Broche Pérez
Ana María Mederos Herrera
Epidemiological, clinical and imaging profile of Multiple Sclerosis
Medisur
esclerosis múltiple
epidemiología
estudio observacional
title Epidemiological, clinical and imaging profile of Multiple Sclerosis
title_full Epidemiological, clinical and imaging profile of Multiple Sclerosis
title_fullStr Epidemiological, clinical and imaging profile of Multiple Sclerosis
title_full_unstemmed Epidemiological, clinical and imaging profile of Multiple Sclerosis
title_short Epidemiological, clinical and imaging profile of Multiple Sclerosis
title_sort epidemiological clinical and imaging profile of multiple sclerosis
topic esclerosis múltiple
epidemiología
estudio observacional
url http://medisur.sld.cu/index.php/medisur/article/view/5254
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