Estimation of causal effects of a time-varying exposure at multiple time points through multivariable mendelian randomization.
Mendelian Randomisation (MR) is a powerful tool in epidemiology that can be used to estimate the causal effect of an exposure on an outcome in the presence of unobserved confounding, by utilising genetic variants as instrumental variables (IVs) for the exposure. The effect estimates obtained from MR...
Saved in:
| Main Authors: | Eleanor Sanderson, Tom G Richardson, Tim T Morris, Kate Tilling, George Davey Smith |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2022-07-01
|
| Series: | PLoS Genetics |
| Online Access: | https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1010290&type=printable |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Evaluating the relationship between circulating lipoprotein lipids and apolipoproteins with risk of coronary heart disease: A multivariable Mendelian randomisation analysis.
by: Tom G Richardson, et al.
Published: (2020-03-01) -
Causal mediation analysis for time-varying heritable risk factors with Mendelian randomization
by: Zixuan Wu, et al.
Published: (2025-07-01) -
Estimating and visualising multivariable Mendelian randomization analyses within a radial framework.
by: Wes Spiller, et al.
Published: (2024-12-01) -
Investigating the causal effects of childhood and adulthood adiposity on later life mental health outcome: a Mendelian randomization study
by: Sweta Pathak, et al.
Published: (2025-01-01) -
Associations between insomnia and pregnancy and perinatal outcomes: Evidence from mendelian randomization and multivariable regression analyses.
by: Qian Yang, et al.
Published: (2022-09-01)