A 36-Year-Old Renal Transplant Recipient Female with Leg Ulcer: A Case Report and Brief Review

Background. Opportunistic infections are common in organ transplant recipients. After 6 months of transplantation, patients have the highest risk of opportunistic infections such as cryptococcosis. Case Presentation. The report presents the case of a 36-year-old female renal transplant recipient, wi...

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Main Authors: Ali Monfared, Eftekhari Hojat, Seyed Alireza Mesbah, Abbas Darjani, Seyyede Zeinab Azimi
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Case Reports in Infectious Diseases
Online Access:http://dx.doi.org/10.1155/2018/5086501
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author Ali Monfared
Eftekhari Hojat
Seyed Alireza Mesbah
Abbas Darjani
Seyyede Zeinab Azimi
author_facet Ali Monfared
Eftekhari Hojat
Seyed Alireza Mesbah
Abbas Darjani
Seyyede Zeinab Azimi
author_sort Ali Monfared
collection DOAJ
description Background. Opportunistic infections are common in organ transplant recipients. After 6 months of transplantation, patients have the highest risk of opportunistic infections such as cryptococcosis. Case Presentation. The report presents the case of a 36-year-old female renal transplant recipient, with complaints of few subcutaneous painful and warm nodules and large, warm, erythematous, nontender plaques on the mildly edematous right leg and ankle. Incisional biopsy of the subcutaneous nodule over the leg showed panniculitis with small- to medium-sized vasculitis associated with round yeast forms, and culture of the fragments revealed C. neoformans var. grubii. Conclusions. This article also reviews in brief the treatment of this rare complication. Reviewing the literature showed that since the cryptococcal cutaneous lesions are often nonspecific, the clinical picture solely is not enough to construct a definite diagnosis and there must be a high clinical suspicion.
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institution Kabale University
issn 2090-6625
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language English
publishDate 2018-01-01
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series Case Reports in Infectious Diseases
spelling doaj-art-1cfb0e76f464457b9f83a86a5455ee882025-02-03T01:30:10ZengWileyCase Reports in Infectious Diseases2090-66252090-66332018-01-01201810.1155/2018/50865015086501A 36-Year-Old Renal Transplant Recipient Female with Leg Ulcer: A Case Report and Brief ReviewAli Monfared0Eftekhari Hojat1Seyed Alireza Mesbah2Abbas Darjani3Seyyede Zeinab Azimi4Department of Nephrology, Urology Research Center, Razi Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, IranDepartment of Dermatology, Skin Research Center, Razi Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, IranRazi Pathobiology Laboratory, Rasht, IranDepartment of Dermatology, Skin Research Center, Razi Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, IranDepartment of Dermatology, Skin Research Center, Razi Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, IranBackground. Opportunistic infections are common in organ transplant recipients. After 6 months of transplantation, patients have the highest risk of opportunistic infections such as cryptococcosis. Case Presentation. The report presents the case of a 36-year-old female renal transplant recipient, with complaints of few subcutaneous painful and warm nodules and large, warm, erythematous, nontender plaques on the mildly edematous right leg and ankle. Incisional biopsy of the subcutaneous nodule over the leg showed panniculitis with small- to medium-sized vasculitis associated with round yeast forms, and culture of the fragments revealed C. neoformans var. grubii. Conclusions. This article also reviews in brief the treatment of this rare complication. Reviewing the literature showed that since the cryptococcal cutaneous lesions are often nonspecific, the clinical picture solely is not enough to construct a definite diagnosis and there must be a high clinical suspicion.http://dx.doi.org/10.1155/2018/5086501
spellingShingle Ali Monfared
Eftekhari Hojat
Seyed Alireza Mesbah
Abbas Darjani
Seyyede Zeinab Azimi
A 36-Year-Old Renal Transplant Recipient Female with Leg Ulcer: A Case Report and Brief Review
Case Reports in Infectious Diseases
title A 36-Year-Old Renal Transplant Recipient Female with Leg Ulcer: A Case Report and Brief Review
title_full A 36-Year-Old Renal Transplant Recipient Female with Leg Ulcer: A Case Report and Brief Review
title_fullStr A 36-Year-Old Renal Transplant Recipient Female with Leg Ulcer: A Case Report and Brief Review
title_full_unstemmed A 36-Year-Old Renal Transplant Recipient Female with Leg Ulcer: A Case Report and Brief Review
title_short A 36-Year-Old Renal Transplant Recipient Female with Leg Ulcer: A Case Report and Brief Review
title_sort 36 year old renal transplant recipient female with leg ulcer a case report and brief review
url http://dx.doi.org/10.1155/2018/5086501
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