Pediatric mechanical circulatory support: pathophysiology of pediatric hemostasis and postoperative management algorithms

Chronic heart failure (CHF) against the background of congenital heart disease, mostly in early childhood, or various forms of cardiomyopathies, more common in teenage age, represents an important cause of morbidity and mortality in the pediatric population [1, 2]. Due to the increase in the number...

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Main Authors: N. N. Koloskova, T. A. Khalilulin, D. V. Ryabtsev, V. N. Poptsov
Format: Article
Language:Russian
Published: Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov 2023-04-01
Series:Вестник трансплантологии и искусственных органов
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Online Access:https://journal.transpl.ru/vtio/article/view/1569
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author N. N. Koloskova
T. A. Khalilulin
D. V. Ryabtsev
V. N. Poptsov
author_facet N. N. Koloskova
T. A. Khalilulin
D. V. Ryabtsev
V. N. Poptsov
author_sort N. N. Koloskova
collection DOAJ
description Chronic heart failure (CHF) against the background of congenital heart disease, mostly in early childhood, or various forms of cardiomyopathies, more common in teenage age, represents an important cause of morbidity and mortality in the pediatric population [1, 2]. Due to the increase in the number of patients suffering from refractory end-stage CHF over the last two decades, and the current shortage of donor organs in pediatric practice, the issue of long-term mechanical circulatory support (MCS) is becoming increasingly a pressing problem. Patient management is a multidisciplinary task, since prolonged use of anticoagulant and antiplatelet therapy to prevent ventricular thrombosis has potentially life-threatening complications - acute hemorrhagic stroke and bleeding of varying severity.
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institution DOAJ
issn 1995-1191
language Russian
publishDate 2023-04-01
publisher Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov
record_format Article
series Вестник трансплантологии и искусственных органов
spelling doaj-art-1ceeea0b6e1f40f19001f17280a1e41a2025-08-20T03:20:51ZrusFederal Research Center of Transplantology and Artificial Organs named after V.I.ShumakovВестник трансплантологии и искусственных органов1995-11912023-04-01251909810.15825/1995-1191-2023-1-90-981159Pediatric mechanical circulatory support: pathophysiology of pediatric hemostasis and postoperative management algorithmsN. N. Koloskova0T. A. Khalilulin1D. V. Ryabtsev2V. N. Poptsov3Shumakov National Medical Research Center of Transplantology and Artificial OrgansShumakov National Medical Research Center of Transplantology and Artificial Organs; Sechenov UniversityShumakov National Medical Research Center of Transplantology and Artificial OrgansShumakov National Medical Research Center of Transplantology and Artificial OrgansChronic heart failure (CHF) against the background of congenital heart disease, mostly in early childhood, or various forms of cardiomyopathies, more common in teenage age, represents an important cause of morbidity and mortality in the pediatric population [1, 2]. Due to the increase in the number of patients suffering from refractory end-stage CHF over the last two decades, and the current shortage of donor organs in pediatric practice, the issue of long-term mechanical circulatory support (MCS) is becoming increasingly a pressing problem. Patient management is a multidisciplinary task, since prolonged use of anticoagulant and antiplatelet therapy to prevent ventricular thrombosis has potentially life-threatening complications - acute hemorrhagic stroke and bleeding of varying severity.https://journal.transpl.ru/vtio/article/view/1569heart failure in childrenlong-term mechanical circulatory supportanticoagulant therapyantiplatelet therapy
spellingShingle N. N. Koloskova
T. A. Khalilulin
D. V. Ryabtsev
V. N. Poptsov
Pediatric mechanical circulatory support: pathophysiology of pediatric hemostasis and postoperative management algorithms
Вестник трансплантологии и искусственных органов
heart failure in children
long-term mechanical circulatory support
anticoagulant therapy
antiplatelet therapy
title Pediatric mechanical circulatory support: pathophysiology of pediatric hemostasis and postoperative management algorithms
title_full Pediatric mechanical circulatory support: pathophysiology of pediatric hemostasis and postoperative management algorithms
title_fullStr Pediatric mechanical circulatory support: pathophysiology of pediatric hemostasis and postoperative management algorithms
title_full_unstemmed Pediatric mechanical circulatory support: pathophysiology of pediatric hemostasis and postoperative management algorithms
title_short Pediatric mechanical circulatory support: pathophysiology of pediatric hemostasis and postoperative management algorithms
title_sort pediatric mechanical circulatory support pathophysiology of pediatric hemostasis and postoperative management algorithms
topic heart failure in children
long-term mechanical circulatory support
anticoagulant therapy
antiplatelet therapy
url https://journal.transpl.ru/vtio/article/view/1569
work_keys_str_mv AT nnkoloskova pediatricmechanicalcirculatorysupportpathophysiologyofpediatrichemostasisandpostoperativemanagementalgorithms
AT takhalilulin pediatricmechanicalcirculatorysupportpathophysiologyofpediatrichemostasisandpostoperativemanagementalgorithms
AT dvryabtsev pediatricmechanicalcirculatorysupportpathophysiologyofpediatrichemostasisandpostoperativemanagementalgorithms
AT vnpoptsov pediatricmechanicalcirculatorysupportpathophysiologyofpediatrichemostasisandpostoperativemanagementalgorithms