The Effects of Pitavastatin on Nuclear Factor-Kappa B and ICAM-1 in Human Saphenous Vein Graft Endothelial Culture

The Effects of Pitavastatin on Nuclear Factor-Kappa B and ICAM-1 in Human Saphenous Vein Graft Endothelial Culture

Objective. To study pitavastatin’s effects on nuclear factor-kappa B (NF-κB ) and adhesion molecules in human saphenous vein graft endothelial culture indicating its pleotropic properties. Materials and Method. Low-dose (0.1 μM/L) and high-dose (1μM/L) pitavastatin calcium were administered as a fro...

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Bibliographic Details
Main Authors: Bulent Demir, Burak Onal, Sibel Ozyazgan, Esra Demir, Vedat Bakuy, Ahmet Gokhan Akkan
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Cardiovascular Therapeutics
Online Access:http://dx.doi.org/10.1155/2019/2549432
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