Throw out an oligopeptide to catch a protein: Deep learning and natural language processing-screened tripeptide PSP promotes Osteolectin-mediated vascularized bone regeneration

Throw out an oligopeptide to catch a protein: Deep learning and natural language processing-screened tripeptide PSP promotes Osteolectin-mediated vascularized bone regeneration

Angiogenesis is imperative for bone regeneration, yet the conventional cytokine therapies have been constrained by prohibitive costs and safety apprehensions. It is urgent to develop a safer and more efficient therapeutic alternative. Herein, utilizing the methodologies of Deep Learning (DL) and Nat...

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Bibliographic Details
Main Authors: Yu Chen, Long Chen, Jinyang Wu, Xiaofeng Xu, Chengshuai Yang, Yong Zhang, Xinrong Chen, Kaili Lin, Shilei Zhang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-04-01
Series:Bioactive Materials
Subjects:
Deep learning
Natural language processing
Bioactive peptides
Vascular-osteo communication
Osteolectin
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X2400495X
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