Strains of Rodents and the Pharmacology of Learning and Memory

Mendelian genetic tools have extensively been used to improve the description of the pharmacological mechanisms involved in learning and memory. The first part of this short review describes experiments involving the bidirectional selection of rats or mice for extreme behavioral characteristics or f...

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Bibliographic Details
Main Authors: Martine Ammassari-Teule, Claudio Castellano
Format: Article
Language:English
Published: Wiley 2004-01-01
Series:Neural Plasticity
Online Access:http://dx.doi.org/10.1155/NP.2004.205
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Summary:Mendelian genetic tools have extensively been used to improve the description of the pharmacological mechanisms involved in learning and memory. The first part of this short review describes experiments involving the bidirectional selection of rats or mice for extreme behavioral characteristics or for sensitivity to pharmacological treatments. The second part focuses specifically on inbreeding. In conclusion, the advantages and the limits of a Mendelian pharmacogenetic approach of learning and memory are discussed.
ISSN:2090-5904
1687-5443