Leiomodin creates a leaky cap at the pointed end of actin-thin filaments.
Improper lengths of actin-thin filaments are associated with altered contractile activity and lethal myopathies. Leiomodin, a member of the tropomodulin family of proteins, is critical in thin filament assembly and maintenance; however, its role is under dispute. Using nuclear magnetic resonance dat...
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Main Authors: | Dmitri Tolkatchev, Garry E Smith, Lauren E Schultz, Mert Colpan, Gregory L Helms, John R Cort, Carol C Gregorio, Alla S Kostyukova |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2020-09-01
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Series: | PLoS Biology |
Online Access: | https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3000848&type=printable |
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