Reconstruction Using Frozen Autograft for Disseminated Phosphaturic Mesenchymal Tumor of the Humerus after a Pathological Fracture

Phosphaturic mesenchymal tumors (PMTs) that cause tumor-induced osteomalacia (TIO) occur commonly in the bone with a small and nonaggressive appearance. Here, we report the case of a 67-year-old man with disseminated PMT in the humerus after a pathological fracture. Liquid nitrogen was used as an ad...

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Main Authors: Hiroshi Kobayashi, Toshihide Hirai, Naohiro Makise, Tetsuo Ushiku, Nobuaki Ito, Minae Koga, Masachika Ikegami, Yusuke Shinoda, Toru Akiyama, Sakae Tanaka
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Case Reports in Orthopedics
Online Access:http://dx.doi.org/10.1155/2019/3015675
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author Hiroshi Kobayashi
Toshihide Hirai
Naohiro Makise
Tetsuo Ushiku
Nobuaki Ito
Minae Koga
Masachika Ikegami
Yusuke Shinoda
Toru Akiyama
Sakae Tanaka
author_facet Hiroshi Kobayashi
Toshihide Hirai
Naohiro Makise
Tetsuo Ushiku
Nobuaki Ito
Minae Koga
Masachika Ikegami
Yusuke Shinoda
Toru Akiyama
Sakae Tanaka
author_sort Hiroshi Kobayashi
collection DOAJ
description Phosphaturic mesenchymal tumors (PMTs) that cause tumor-induced osteomalacia (TIO) occur commonly in the bone with a small and nonaggressive appearance. Here, we report the case of a 67-year-old man with disseminated PMT in the humerus after a pathological fracture. Liquid nitrogen was used as an adjuvant therapy after curettage of the tumor, and the frozen autograft, using a pedicle freezing method, conserved the function of the shoulder joint. To our knowledge, this is the first case of a disseminated PMT in the bone that was treated with a frozen autograft, and this treatment method may be effective for cases in which curettage for PMT in the bone would be inevitably inadequate.
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id doaj-art-1cb8daaac56347318ff9baed1a82742d
institution OA Journals
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language English
publishDate 2019-01-01
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series Case Reports in Orthopedics
spelling doaj-art-1cb8daaac56347318ff9baed1a82742d2025-08-20T02:01:43ZengWileyCase Reports in Orthopedics2090-67492090-67572019-01-01201910.1155/2019/30156753015675Reconstruction Using Frozen Autograft for Disseminated Phosphaturic Mesenchymal Tumor of the Humerus after a Pathological FractureHiroshi Kobayashi0Toshihide Hirai1Naohiro Makise2Tetsuo Ushiku3Nobuaki Ito4Minae Koga5Masachika Ikegami6Yusuke Shinoda7Toru Akiyama8Sakae Tanaka9Department of Orthopaedic Surgery, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, JapanDepartment of Orthopaedic Surgery, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, JapanDepartment of Pathology, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, JapanDepartment of Pathology, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, JapanDepartment of Nephrology and Endocrinology, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, JapanDepartment of Nephrology and Endocrinology, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, JapanDepartment of Orthopaedic Surgery, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, JapanDepartment of Orthopaedic Surgery, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, JapanDepartment of Orthopaedic Surgery, Saitama Medical Center, Jichi Medical University, 1-847 Amanuma, Omiya-ku, Saitama 330-8503, JapanDepartment of Orthopaedic Surgery, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, JapanPhosphaturic mesenchymal tumors (PMTs) that cause tumor-induced osteomalacia (TIO) occur commonly in the bone with a small and nonaggressive appearance. Here, we report the case of a 67-year-old man with disseminated PMT in the humerus after a pathological fracture. Liquid nitrogen was used as an adjuvant therapy after curettage of the tumor, and the frozen autograft, using a pedicle freezing method, conserved the function of the shoulder joint. To our knowledge, this is the first case of a disseminated PMT in the bone that was treated with a frozen autograft, and this treatment method may be effective for cases in which curettage for PMT in the bone would be inevitably inadequate.http://dx.doi.org/10.1155/2019/3015675
spellingShingle Hiroshi Kobayashi
Toshihide Hirai
Naohiro Makise
Tetsuo Ushiku
Nobuaki Ito
Minae Koga
Masachika Ikegami
Yusuke Shinoda
Toru Akiyama
Sakae Tanaka
Reconstruction Using Frozen Autograft for Disseminated Phosphaturic Mesenchymal Tumor of the Humerus after a Pathological Fracture
Case Reports in Orthopedics
title Reconstruction Using Frozen Autograft for Disseminated Phosphaturic Mesenchymal Tumor of the Humerus after a Pathological Fracture
title_full Reconstruction Using Frozen Autograft for Disseminated Phosphaturic Mesenchymal Tumor of the Humerus after a Pathological Fracture
title_fullStr Reconstruction Using Frozen Autograft for Disseminated Phosphaturic Mesenchymal Tumor of the Humerus after a Pathological Fracture
title_full_unstemmed Reconstruction Using Frozen Autograft for Disseminated Phosphaturic Mesenchymal Tumor of the Humerus after a Pathological Fracture
title_short Reconstruction Using Frozen Autograft for Disseminated Phosphaturic Mesenchymal Tumor of the Humerus after a Pathological Fracture
title_sort reconstruction using frozen autograft for disseminated phosphaturic mesenchymal tumor of the humerus after a pathological fracture
url http://dx.doi.org/10.1155/2019/3015675
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