Determination of Pendimethalin Dynamic Residual Distribution in Crucian Carp Tissues and Associated Risk Assessment
Pendimethalin has been considered a moderately to extremely toxic compound for fish and aquatic organism. This study developed the determination of dynamic residual distribution for pendimethalin in crucian carp tissues (muscle, liver, kidney, gill, and blood) under semistatic exposure system by hig...
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | International Journal of Analytical Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2021/9984230 |
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| author | Lu Qiao Na Yuan Gang Han Bo Cheng Defu Zhang Jinlong Song Yingchun Mu |
| author_facet | Lu Qiao Na Yuan Gang Han Bo Cheng Defu Zhang Jinlong Song Yingchun Mu |
| author_sort | Lu Qiao |
| collection | DOAJ |
| description | Pendimethalin has been considered a moderately to extremely toxic compound for fish and aquatic organism. This study developed the determination of dynamic residual distribution for pendimethalin in crucian carp tissues (muscle, liver, kidney, gill, and blood) under semistatic exposure system by high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) method. The pendimethalin residues in various fish tissues increased initially and then decreased, and the residue amount of pendimethalin varied from tissue to tissue of crucian carp. Particularly, the pendimethalin accumulation in most fish tissues made significant decreases at two-time points. Pendimethalin was initially absorbed and enriched by fish body, and then partial pendimethalin was discharged into the outside environment through the metabolism function of crucian carp. The residue levels of pendimethalin distributed in crucian carp were ranked in the following decreasing order: liver > kidney > gill or muscle > blood, attributed to the fact that pendimethalin tends to accumulate in lipid-rich tissues of fish. Risk assessment results indicated that the chronic risk from dietary exposure to pendimethalin through crucian carp consumption for Chinese residents was acceptable, along with a lower estimated exposure dose (EED) than acceptable daily intake (ADI) and risk quotient (RQ) < 1. This study performed the first analysis for pendimethalin residual distribution in crucian carp tissues under semistatic exposure condition and provided a reference for pollution control and risk assessment of pendimethalin aimed at aquatic products. |
| format | Article |
| id | doaj-art-1cb4b7a5cd074df5a0424069bf18358b |
| institution | Kabale University |
| issn | 1687-8760 1687-8779 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Analytical Chemistry |
| spelling | doaj-art-1cb4b7a5cd074df5a0424069bf18358b2025-02-03T07:24:23ZengWileyInternational Journal of Analytical Chemistry1687-87601687-87792021-01-01202110.1155/2021/99842309984230Determination of Pendimethalin Dynamic Residual Distribution in Crucian Carp Tissues and Associated Risk AssessmentLu Qiao0Na Yuan1Gang Han2Bo Cheng3Defu Zhang4Jinlong Song5Yingchun Mu6Key Laboratory of Control of Quality and Safety for Aquatic Products (Ministry of Agriculture and Rural Affairs), Chinese Academy of Fishery Sciences, Beijing 100141, ChinaCollege of Food Science and Engineering, Bohai University, Jinzhou, Liaoning 121000, ChinaKey Laboratory of Control of Quality and Safety for Aquatic Products (Ministry of Agriculture and Rural Affairs), Chinese Academy of Fishery Sciences, Beijing 100141, ChinaKey Laboratory of Control of Quality and Safety for Aquatic Products (Ministry of Agriculture and Rural Affairs), Chinese Academy of Fishery Sciences, Beijing 100141, ChinaCollege of Food Science and Engineering, Bohai University, Jinzhou, Liaoning 121000, ChinaKey Laboratory of Control of Quality and Safety for Aquatic Products (Ministry of Agriculture and Rural Affairs), Chinese Academy of Fishery Sciences, Beijing 100141, ChinaKey Laboratory of Control of Quality and Safety for Aquatic Products (Ministry of Agriculture and Rural Affairs), Chinese Academy of Fishery Sciences, Beijing 100141, ChinaPendimethalin has been considered a moderately to extremely toxic compound for fish and aquatic organism. This study developed the determination of dynamic residual distribution for pendimethalin in crucian carp tissues (muscle, liver, kidney, gill, and blood) under semistatic exposure system by high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) method. The pendimethalin residues in various fish tissues increased initially and then decreased, and the residue amount of pendimethalin varied from tissue to tissue of crucian carp. Particularly, the pendimethalin accumulation in most fish tissues made significant decreases at two-time points. Pendimethalin was initially absorbed and enriched by fish body, and then partial pendimethalin was discharged into the outside environment through the metabolism function of crucian carp. The residue levels of pendimethalin distributed in crucian carp were ranked in the following decreasing order: liver > kidney > gill or muscle > blood, attributed to the fact that pendimethalin tends to accumulate in lipid-rich tissues of fish. Risk assessment results indicated that the chronic risk from dietary exposure to pendimethalin through crucian carp consumption for Chinese residents was acceptable, along with a lower estimated exposure dose (EED) than acceptable daily intake (ADI) and risk quotient (RQ) < 1. This study performed the first analysis for pendimethalin residual distribution in crucian carp tissues under semistatic exposure condition and provided a reference for pollution control and risk assessment of pendimethalin aimed at aquatic products.http://dx.doi.org/10.1155/2021/9984230 |
| spellingShingle | Lu Qiao Na Yuan Gang Han Bo Cheng Defu Zhang Jinlong Song Yingchun Mu Determination of Pendimethalin Dynamic Residual Distribution in Crucian Carp Tissues and Associated Risk Assessment International Journal of Analytical Chemistry |
| title | Determination of Pendimethalin Dynamic Residual Distribution in Crucian Carp Tissues and Associated Risk Assessment |
| title_full | Determination of Pendimethalin Dynamic Residual Distribution in Crucian Carp Tissues and Associated Risk Assessment |
| title_fullStr | Determination of Pendimethalin Dynamic Residual Distribution in Crucian Carp Tissues and Associated Risk Assessment |
| title_full_unstemmed | Determination of Pendimethalin Dynamic Residual Distribution in Crucian Carp Tissues and Associated Risk Assessment |
| title_short | Determination of Pendimethalin Dynamic Residual Distribution in Crucian Carp Tissues and Associated Risk Assessment |
| title_sort | determination of pendimethalin dynamic residual distribution in crucian carp tissues and associated risk assessment |
| url | http://dx.doi.org/10.1155/2021/9984230 |
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