Anti-fibrosis effect and its mechanism of atractylenolide III on post-traumatic extending knee joint contracture in rats

Anti-fibrosis effect and its mechanism of atractylenolide III on post-traumatic extending knee joint contracture in rats

Objectives: Atractylenolide III (ATL III) is the major bioactive component found in Atractylodes macrocephala, which has shown a range of benefits in pharmacological studies, including neuroprotection, anti-neuroinflammatory properties, antioxidant effects, anti-allergic effects, anti-cancer propert...

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Main Authors: Bin-Bin Zhang, Lei Xu, Quan-Bing Zhang, Yan Wang, Chen Chen, Jin-Niu Zhang, Xian-Liang Rao, Bing-Jing Zhu, Xue-Ming Li, De-Ting Zhu, Xiu-Li Kan, Jing Mao, Run Zhang, Yun Zhou
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Experimental Gerontology
Subjects:
TL III
Sirt1
Smad3
Deacetylation
Knee joint fibrosis
Online Access:http://www.sciencedirect.com/science/article/pii/S0531556525000361
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