Computational drug discovery pipelines identify NAMPT as a therapeutic target in neuroendocrine prostate cancer
Abstract Neuroendocrine prostate cancer (NEPC) is an aggressive advanced subtype of prostate cancer that exhibits poor prognosis and broad resistance to therapies. Currently, few treatment options are available, highlighting a need for new therapeutics to help curb the high mortality rates of this d...
Saved in:
| Main Authors: | Weijie Zhang, Adam Lee, Lauren Lee, Scott M. Dehm, R. Stephanie Huang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2024-09-01
|
| Series: | Clinical and Translational Science |
| Online Access: | https://doi.org/10.1111/cts.70030 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Therapeutic Exploitation of Neuroendocrine Transdifferentiation Drivers in Prostate Cancer
by: Zoe R. Maylin, et al.
Published: (2024-12-01) -
Regulation of Regenerative Periodontal Healing by NAMPT
by: Marjan Nokhbehsaim, et al.
Published: (2013-01-01) -
A multilevel screening pipeline in zebrafish identifies therapeutic drugs for GAN
by: Léa Lescouzères, et al.
Published: (2023-05-01) -
NEDD4 E3 ligase-catalyzed NAMPT ubiquitination and autophagy activation are essential for pyroptosis-independent NAMPT secretion in human monocytes
by: Marisela Rodriguez, et al.
Published: (2025-03-01) -
Efficacy of NAMPT inhibition in T-cell acute lymphoblastic leukemia
by: Chelsea Vrana, et al.
Published: (2025-01-01)