Intranasal Inoculation of Cationic Crosslinked Carbon Dots‐Adjuvanted Respiratory Syncytial Virus F Subunit Vaccine Elicits Mucosal and Systemic Humoral and Cellular Immunity

Intranasal Inoculation of Cationic Crosslinked Carbon Dots‐Adjuvanted Respiratory Syncytial Virus F Subunit Vaccine Elicits Mucosal and Systemic Humoral and Cellular Immunity

ABSTRACT Respiratory syncytial virus (RSV) causes severe acute lower respiratory tract infections, especially in infants and the elderly. Developing an RSV vaccine that promotes a robust mucosal immune response is necessary to successfully prevent viral transmission and the development of severe dis...

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Main Authors: Hong Lei, Aqu Alu, Jingyun Yang, Cai He, Jie Shi, Weiqi Hong, Dandan Peng, Yu Zhang, Jian Liu, Furong Qin, Xiya Huang, Chunjun Ye, Lijiao Pei, Xuemei He, Hong Yan, Guangwen Lu, Xiangrong Song, Xiawei Wei, Yuquan Wei
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:MedComm
Subjects:
respiratory syncytial virus (RSV)
intranasal vaccine
crosslinked carbon dot (CCD)
adjuvant
mucosal immunity
Online Access:https://doi.org/10.1002/mco2.70146
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