Neonatal Brain MRI and Motor Outcome at School Age in Children with Neonatal Encephalopathy: A Review of Personal Experience
The aim of this paper is to review (i) the spectrum of neuromotor function at school age in children who had been born full-term and presented with neonatal encephalopathy (NE) and low Apgar scores and (ii) the relation between the presence/absence of such difficulties and neonatal brain MRI. Motor...
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Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2003-01-01
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Series: | Neural Plasticity |
Online Access: | http://dx.doi.org/10.1155/NP.2003.51 |
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Summary: | The aim of this paper is to review (i) the
spectrum of neuromotor function at school age in
children who had been born full-term and
presented with neonatal encephalopathy (NE) and
low Apgar scores and (ii) the relation between the
presence/absence of such difficulties and neonatal
brain MRI. Motor outcome appears to be mainly
related to the severity of basal ganglia and
internal capsule involvement. Severe basal ganglia
lesions were always associated with the most
severe outcome, microcephaly, tetraplegia, and
severe global delay, whereas more discrete basal
ganglia lesions were associated with athetoid
cerebral palsy, with normal cognitive development
or minor neuro-motor abnormalities. White
matter lesions were associated with abnormal
motor outcome only if the internal capsule was
involved. Children with moderate white matter
changes but normal internal capsule, had normal
motor outcome at school age. |
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ISSN: | 2090-5904 1687-5443 |