Association of Fibroblast Growth Factor 23 and Calcium in Chronic Kidney Disease Patients
Chronic kidney disease (CKD) is a growing international health concern with elevating mortality rate in the world today and it is generally a progressive and irreversible issue. It is defined by changes in kidney shape, function, or both lasting at least three months. Renal disease is commonly asso...
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middle technical university
2022-11-01
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| Series: | Journal of Techniques |
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| Online Access: | https://journal.mtu.edu.iq/index.php/MTU/article/view/656 |
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| author | Ghaith Hamza Kamil Mohammed Mezher Hussein Raya Ezzat Maroof |
| author_facet | Ghaith Hamza Kamil Mohammed Mezher Hussein Raya Ezzat Maroof |
| author_sort | Ghaith Hamza Kamil |
| collection | DOAJ |
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Chronic kidney disease (CKD) is a growing international health concern with elevating mortality rate in the world today and it is generally a progressive and irreversible issue. It is defined by changes in kidney shape, function, or both lasting at least three months. Renal disease is commonly associated with Abnormalities of minerals and electrolyte. Levels of Ca change and the FGF23 increase early in CKD. This study was designed to show the Correlation between FGF23 and Ca in chronic kidney disease patients. One hundred blood samples (57males and 43 females) from CKD patients have been gathered from Al-Yarmouk Teaching Hospital, Baghdad Teaching Hospital and Al-Karama Teaching Hospital during the period from December 2021 to March 2022 besides 50 samples as apparently healthy control. The age range in the current study was at 33-75 years for CKD patient and 30-65 years for control. The fibroblast growth factor 23 was screened by an ELISA method and serum Calcium, by cobas c111 analyze. Ca, FGF23 is statistically highly significant at p-value =0.001. The receiver operation characteristic (ROC) curve results revealed that the sensitivity and specificity for FGF23 was 100%. The conclusion of the current study shows that the. FGF 23 was high in all CKD patients and Ca was high in two patients, normal in thirty-seven patients, and decreased in sixty-one patients.
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| format | Article |
| id | doaj-art-1c60c110c32b479ca38efefba1f514c7 |
| institution | Kabale University |
| issn | 1818-653X 2708-8383 |
| language | English |
| publishDate | 2022-11-01 |
| publisher | middle technical university |
| record_format | Article |
| series | Journal of Techniques |
| spelling | doaj-art-1c60c110c32b479ca38efefba1f514c72025-01-19T11:07:07Zengmiddle technical universityJournal of Techniques1818-653X2708-83832022-11-014Special Issue10.51173/jt.v4i33.656Association of Fibroblast Growth Factor 23 and Calcium in Chronic Kidney Disease PatientsGhaith Hamza Kamil0Mohammed Mezher Hussein1Raya Ezzat Maroof 2College of Health & Medical Technology - Baghdad, Middle Technical University, Baghdad, IraqCollege of Health & Medical Technology - Baghdad, Middle Technical University, Baghdad, IraqCollege of Health & Medical Technology - Baghdad, Middle Technical University, Baghdad, Iraq Chronic kidney disease (CKD) is a growing international health concern with elevating mortality rate in the world today and it is generally a progressive and irreversible issue. It is defined by changes in kidney shape, function, or both lasting at least three months. Renal disease is commonly associated with Abnormalities of minerals and electrolyte. Levels of Ca change and the FGF23 increase early in CKD. This study was designed to show the Correlation between FGF23 and Ca in chronic kidney disease patients. One hundred blood samples (57males and 43 females) from CKD patients have been gathered from Al-Yarmouk Teaching Hospital, Baghdad Teaching Hospital and Al-Karama Teaching Hospital during the period from December 2021 to March 2022 besides 50 samples as apparently healthy control. The age range in the current study was at 33-75 years for CKD patient and 30-65 years for control. The fibroblast growth factor 23 was screened by an ELISA method and serum Calcium, by cobas c111 analyze. Ca, FGF23 is statistically highly significant at p-value =0.001. The receiver operation characteristic (ROC) curve results revealed that the sensitivity and specificity for FGF23 was 100%. The conclusion of the current study shows that the. FGF 23 was high in all CKD patients and Ca was high in two patients, normal in thirty-seven patients, and decreased in sixty-one patients. https://journal.mtu.edu.iq/index.php/MTU/article/view/656Chronic kidney diseaseCalciumFibroblast growth factor 23 |
| spellingShingle | Ghaith Hamza Kamil Mohammed Mezher Hussein Raya Ezzat Maroof Association of Fibroblast Growth Factor 23 and Calcium in Chronic Kidney Disease Patients Journal of Techniques Chronic kidney disease Calcium Fibroblast growth factor 23 |
| title | Association of Fibroblast Growth Factor 23 and Calcium in Chronic Kidney Disease Patients |
| title_full | Association of Fibroblast Growth Factor 23 and Calcium in Chronic Kidney Disease Patients |
| title_fullStr | Association of Fibroblast Growth Factor 23 and Calcium in Chronic Kidney Disease Patients |
| title_full_unstemmed | Association of Fibroblast Growth Factor 23 and Calcium in Chronic Kidney Disease Patients |
| title_short | Association of Fibroblast Growth Factor 23 and Calcium in Chronic Kidney Disease Patients |
| title_sort | association of fibroblast growth factor 23 and calcium in chronic kidney disease patients |
| topic | Chronic kidney disease Calcium Fibroblast growth factor 23 |
| url | https://journal.mtu.edu.iq/index.php/MTU/article/view/656 |
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