Tuning gut microbiota by advanced nanotechnology
Gut microbiota reveals fundamental mechanisms of health and disease, and its modulation has important applications in biomedicine. Traditional modulation methods ( e.g. diet, antibiotics, and probiotics) suffer from drug resistance, poor targeting, and low efficiency. Nanotechnology has become an at...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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IOP Publishing
2025-01-01
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| Series: | Materials Futures |
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| Online Access: | https://doi.org/10.1088/2752-5724/ada62b |
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| author | Yue Qi Yueyi Wang Xiaofei Wang Hao Zheng Yuan Lu |
| author_facet | Yue Qi Yueyi Wang Xiaofei Wang Hao Zheng Yuan Lu |
| author_sort | Yue Qi |
| collection | DOAJ |
| description | Gut microbiota reveals fundamental mechanisms of health and disease, and its modulation has important applications in biomedicine. Traditional modulation methods ( e.g. diet, antibiotics, and probiotics) suffer from drug resistance, poor targeting, and low efficiency. Nanotechnology has become an attractive option for the precise modulation of gut microbiota due to its targeting and controllability. This review will focus on research progress in nanotechnology to modulate gut microbiota, including the direct use of nanomaterials as antimicrobials, nano-drug delivery systems, and stimulus-responsive nanotechnology. In addition, the applications of nanotechnology to modulate gut microbiota are summarized in terms of healthcare, animal protection, and agricultural development. Finally, the challenges and corresponding solution strategies for nanotechnology modulation are reviewed, and the future development prospects for nanotechnology modulation are summarized. This review provides an important theoretical basis and practical reference for the development of gut microbiota modulation, and promotes the research and application of more precise and efficient microbiota community intervention strategies. |
| format | Article |
| id | doaj-art-1c60413c9f954d00a23a5f4800167b0b |
| institution | Kabale University |
| issn | 2752-5724 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | IOP Publishing |
| record_format | Article |
| series | Materials Futures |
| spelling | doaj-art-1c60413c9f954d00a23a5f4800167b0b2025-01-23T11:05:50ZengIOP PublishingMaterials Futures2752-57242025-01-014101230210.1088/2752-5724/ada62bTuning gut microbiota by advanced nanotechnologyYue Qi0Yueyi Wang1Xiaofei Wang2Hao Zheng3Yuan Lu4https://orcid.org/0000-0003-4500-6230College of Food Science and Nutritional Engineering, China Agricultural University , Beijing 100083, People’s Republic of China; Department of Chemical Engineering, Tsinghua University , Beijing 100084, People’s Republic of China; Key Laboratory of Industrial Biocatalysis, Ministry of Education, Tsinghua University , Beijing 100084, People’s Republic of ChinaCollege of Food Science and Nutritional Engineering, China Agricultural University , Beijing 100083, People’s Republic of China; Department of Chemical Engineering, Tsinghua University , Beijing 100084, People’s Republic of China; Key Laboratory of Industrial Biocatalysis, Ministry of Education, Tsinghua University , Beijing 100084, People’s Republic of ChinaCollege of Food Science and Nutritional Engineering, China Agricultural University , Beijing 100083, People’s Republic of ChinaCollege of Food Science and Nutritional Engineering, China Agricultural University , Beijing 100083, People’s Republic of ChinaDepartment of Chemical Engineering, Tsinghua University , Beijing 100084, People’s Republic of China; Key Laboratory of Industrial Biocatalysis, Ministry of Education, Tsinghua University , Beijing 100084, People’s Republic of ChinaGut microbiota reveals fundamental mechanisms of health and disease, and its modulation has important applications in biomedicine. Traditional modulation methods ( e.g. diet, antibiotics, and probiotics) suffer from drug resistance, poor targeting, and low efficiency. Nanotechnology has become an attractive option for the precise modulation of gut microbiota due to its targeting and controllability. This review will focus on research progress in nanotechnology to modulate gut microbiota, including the direct use of nanomaterials as antimicrobials, nano-drug delivery systems, and stimulus-responsive nanotechnology. In addition, the applications of nanotechnology to modulate gut microbiota are summarized in terms of healthcare, animal protection, and agricultural development. Finally, the challenges and corresponding solution strategies for nanotechnology modulation are reviewed, and the future development prospects for nanotechnology modulation are summarized. This review provides an important theoretical basis and practical reference for the development of gut microbiota modulation, and promotes the research and application of more precise and efficient microbiota community intervention strategies.https://doi.org/10.1088/2752-5724/ada62bnanotechnologygut microbiotamodulationdrug delivery |
| spellingShingle | Yue Qi Yueyi Wang Xiaofei Wang Hao Zheng Yuan Lu Tuning gut microbiota by advanced nanotechnology Materials Futures nanotechnology gut microbiota modulation drug delivery |
| title | Tuning gut microbiota by advanced nanotechnology |
| title_full | Tuning gut microbiota by advanced nanotechnology |
| title_fullStr | Tuning gut microbiota by advanced nanotechnology |
| title_full_unstemmed | Tuning gut microbiota by advanced nanotechnology |
| title_short | Tuning gut microbiota by advanced nanotechnology |
| title_sort | tuning gut microbiota by advanced nanotechnology |
| topic | nanotechnology gut microbiota modulation drug delivery |
| url | https://doi.org/10.1088/2752-5724/ada62b |
| work_keys_str_mv | AT yueqi tuninggutmicrobiotabyadvancednanotechnology AT yueyiwang tuninggutmicrobiotabyadvancednanotechnology AT xiaofeiwang tuninggutmicrobiotabyadvancednanotechnology AT haozheng tuninggutmicrobiotabyadvancednanotechnology AT yuanlu tuninggutmicrobiotabyadvancednanotechnology |