Alleviating symptoms of paediatric acute rhinosinusitis and acute otitis media with otorrhea using nasal-spraying Bacillus probiotics: a randomized controlled trial

Alleviating symptoms of paediatric acute rhinosinusitis and acute otitis media with otorrhea using nasal-spraying Bacillus probiotics: a randomized controlled trial

Abstract Acute rhinosinusitis (ARS) in children may be accompanied by acute otitis media (AOM) which is often associated with bacterial co-infections. These conditions are among the primary reasons that children visit hospitals and require antibiotic treatment. This study evaluated the efficacy of t...

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Bibliographic Details
Main Authors: Thanh Huu Khieu, Dung Phuong Le, Binh Thanh Nguyen, Binh Thanh Ngo, Hong Thi Chu, Duc Minh Truong, Hung Minh Nguyen, Anh Hoa Nguyen, Tung Dinh Pham, Anh Thi Van Nguyen
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Acute
Rhinosinusitis
Otitis media
Nasal-spraying Bacillus spores
Bacterial co-infection
Cytokine
Online Access:https://doi.org/10.1038/s41598-025-87372-2
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