Tuberculous pericarditis due to silicon oxide exposure. A case report with an imaging approach
Abstract Introduction: This is a case report of a patient with tuberculous pericarditis, a rare form of tuberculosis associated with high morbidity and mortality. It contributes to the medical literature, given that it provides a comprehensive review of the imaging approach to this disease. Cas...
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Universidad Nacional de Colombia
2025-01-01
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| Series: | Case Reports |
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| Online Access: | https://revistas.unal.edu.co/index.php/care/article/view/107026 |
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| author | Andrés Felipe Donado-Moré Jorge Ignacio Arrieta-Castaño Lina Fernanda Acevedo-Forero Jorge Alberto Carrillo-Bayona Alejandro Vega-Molina Wilmer Orlando Aponte-Barrios Oscar Andrés Franco-Tavera |
| author_facet | Andrés Felipe Donado-Moré Jorge Ignacio Arrieta-Castaño Lina Fernanda Acevedo-Forero Jorge Alberto Carrillo-Bayona Alejandro Vega-Molina Wilmer Orlando Aponte-Barrios Oscar Andrés Franco-Tavera |
| author_sort | Andrés Felipe Donado-Moré |
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Abstract
Introduction: This is a case report of a patient with tuberculous pericarditis, a rare form of tuberculosis associated with high morbidity and mortality. It contributes to the medical literature, given that it provides a comprehensive review of the imaging approach to this disease.
Case presentation: A 52-year-old man previously exposed to silicon oxide who was referred to the Intensive Care Unit of a quaternary care hospital in the city of Bogotá (Colombia) due to hyperdense pericardial effusion, which was initially considered to have a neoplastic etiology. Imaging studies showed results suggestive of tuberculous pericarditis, prompting a pericardiocentesis, with microbiological and molecular detection studies in pericardial fluid that were negative for Mycobacterium tuberculosis and fungi. The only positive test was adenosine deaminase (ADA), thus raising the suspicion of tuberculous pericarditis. The definitive diagnosis was obtained via pericardial biopsy. Daily oral antituberculosis treatment was administered for 56 days, resulting in a significant improvement in the patient's condition.
Conclusions: Tuberculous pericarditis should be suspected in patients presenting with hemorrhagic pericardial effusion, which can be reliably identified by ultrasound/echocardiography, CT, or MRI. It is recommended to include supportive diagnostic studies such as echocardiography, plain and contrasted CT of the chest, pericardiocentesis with ADA testing of pericardial fluid, and pericardial biopsy as the standard diagnostic approach in cases with clinical suspicion to reach a definitive diagnosis.
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| format | Article |
| id | doaj-art-1c36ceedcaa440e58db04cb2a4bf2369 |
| institution | Kabale University |
| issn | 2462-8522 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Universidad Nacional de Colombia |
| record_format | Article |
| series | Case Reports |
| spelling | doaj-art-1c36ceedcaa440e58db04cb2a4bf23692025-01-24T06:07:09ZengUniversidad Nacional de ColombiaCase Reports2462-85222025-01-0110210.15446/cr.v10n2.107026Tuberculous pericarditis due to silicon oxide exposure. A case report with an imaging approachAndrés Felipe Donado-Moré0https://orcid.org/0000-0003-2189-8756Jorge Ignacio Arrieta-Castaño1https://orcid.org/0000-0002-2301-3758Lina Fernanda Acevedo-Forero2https://orcid.org/0000-0001-8822-0275Jorge Alberto Carrillo-Bayona3https://orcid.org/0000-0003-4150-2915Alejandro Vega-Molina4https://orcid.org/0000-0003-3241-4809Wilmer Orlando Aponte-Barrios5https://orcid.org/0000-0001-9203-8273Oscar Andrés Franco-Tavera6https://orcid.org/0000-0002-9351-4128Universidad Nacional de Colombia – Hospital Universitario Nacional –Departamento de Radiología – Bogotá D. C. – ColombiaUniversidad Nacional de Colombia – Hospital Universitario Nacional –Departamento de Radiología – Bogotá D. C. – ColombiaUniversidad Nacional de Colombia – Hospital Universitario Nacional –Departamento de Radiología – Bogotá D. C. – ColombiaUniversidad Nacional de Colombia – Hospital Universitario Nacional –Departamento de Radiología – Bogotá D. C. – ColombiaUniversidad Nacional de Colombia – Hospital Universitario Nacional –Departamento de Radiología – Bogotá D. C. – ColombiaUniversidad Nacional de Colombia – Hospital Universitario Nacional –Departamento de Radiología – Bogotá D. C. – ColombiaUniversidad Nacional de Colombia – Hospital Universitario Nacional –Departamento de Patología – Bogotá D. C. – Colombia Abstract Introduction: This is a case report of a patient with tuberculous pericarditis, a rare form of tuberculosis associated with high morbidity and mortality. It contributes to the medical literature, given that it provides a comprehensive review of the imaging approach to this disease. Case presentation: A 52-year-old man previously exposed to silicon oxide who was referred to the Intensive Care Unit of a quaternary care hospital in the city of Bogotá (Colombia) due to hyperdense pericardial effusion, which was initially considered to have a neoplastic etiology. Imaging studies showed results suggestive of tuberculous pericarditis, prompting a pericardiocentesis, with microbiological and molecular detection studies in pericardial fluid that were negative for Mycobacterium tuberculosis and fungi. The only positive test was adenosine deaminase (ADA), thus raising the suspicion of tuberculous pericarditis. The definitive diagnosis was obtained via pericardial biopsy. Daily oral antituberculosis treatment was administered for 56 days, resulting in a significant improvement in the patient's condition. Conclusions: Tuberculous pericarditis should be suspected in patients presenting with hemorrhagic pericardial effusion, which can be reliably identified by ultrasound/echocardiography, CT, or MRI. It is recommended to include supportive diagnostic studies such as echocardiography, plain and contrasted CT of the chest, pericardiocentesis with ADA testing of pericardial fluid, and pericardial biopsy as the standard diagnostic approach in cases with clinical suspicion to reach a definitive diagnosis. https://revistas.unal.edu.co/index.php/care/article/view/107026PericardiumPericardial effusionTuberculosisSilicosisPericarditis, Tuberculous |
| spellingShingle | Andrés Felipe Donado-Moré Jorge Ignacio Arrieta-Castaño Lina Fernanda Acevedo-Forero Jorge Alberto Carrillo-Bayona Alejandro Vega-Molina Wilmer Orlando Aponte-Barrios Oscar Andrés Franco-Tavera Tuberculous pericarditis due to silicon oxide exposure. A case report with an imaging approach Case Reports Pericardium Pericardial effusion Tuberculosis Silicosis Pericarditis, Tuberculous |
| title | Tuberculous pericarditis due to silicon oxide exposure. A case report with an imaging approach |
| title_full | Tuberculous pericarditis due to silicon oxide exposure. A case report with an imaging approach |
| title_fullStr | Tuberculous pericarditis due to silicon oxide exposure. A case report with an imaging approach |
| title_full_unstemmed | Tuberculous pericarditis due to silicon oxide exposure. A case report with an imaging approach |
| title_short | Tuberculous pericarditis due to silicon oxide exposure. A case report with an imaging approach |
| title_sort | tuberculous pericarditis due to silicon oxide exposure a case report with an imaging approach |
| topic | Pericardium Pericardial effusion Tuberculosis Silicosis Pericarditis, Tuberculous |
| url | https://revistas.unal.edu.co/index.php/care/article/view/107026 |
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