Immunosuppressive Activity of Size-Controlled PEG-PLGA Nanoparticles Containing Encapsulated Cyclosporine A

Immunosuppressive Activity of Size-Controlled PEG-PLGA Nanoparticles Containing Encapsulated Cyclosporine A

We encapsulated cyclosporine A (CsA) in poly(ethylene glycol)-b-poly(d,l-lactide-co-glycolide) (PEG-PLGA) nanoparticles (NPs) by nanoprecipitation of CsA and PEG-PLGA. The resulting CsA/PEG-PLGA-NPs were <100 nm in diameter with a narrow particle size distribution. The NP size could be controlled...

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Bibliographic Details
Main Authors:	Li Tang, Jamil Azzi, Mincheol Kwon, Marwan Mounayar, Rong Tong, Qian Yin, Robert Moore, Nikolaos Skartsis, Timothy M. Fan, Reza Abdi, Jianjun Cheng
Format:	Article
Language:	English
Published:	Wiley 2012-01-01
Series:	Journal of Transplantation
Online Access:	http://dx.doi.org/10.1155/2012/896141
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