Elastography Method for Reconstruction of Nonlinear Breast Tissue Properties
Elastography is developed as a quantitative approach to imaging linear elastic properties of tissues to detect suspicious tumors. In this paper a nonlinear elastography method is introduced for reconstruction of complex breast tissue properties. The elastic parameters are estimated by optimally mini...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2009-01-01
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| Series: | International Journal of Biomedical Imaging |
| Online Access: | http://dx.doi.org/10.1155/2009/406854 |
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| _version_ | 1832563001324994560 |
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| author | Z. G. Wang Y. Liu G. Wang L. Z. Sun |
| author_facet | Z. G. Wang Y. Liu G. Wang L. Z. Sun |
| author_sort | Z. G. Wang |
| collection | DOAJ |
| description | Elastography is developed as a quantitative approach to imaging linear elastic properties of tissues to detect suspicious tumors. In this paper a nonlinear elastography method is introduced for reconstruction of complex breast tissue properties. The elastic parameters are estimated by optimally minimizing the difference between the computed forces and experimental measures. A nonlinear adjoint method is derived to calculate the gradient of the objective function, which significantly enhances the numerical efficiency and stability. Simulations are conducted on a three-dimensional heterogeneous breast phantom extracting from real imaging including fatty tissue, glandular tissue, and tumors. An
exponential-form of nonlinear material model is applied. The effect of noise is taken into account.
Results demonstrate that the proposed nonlinear method opens the door toward nonlinear elastography
and provides guidelines for future development and clinical application in breast cancer study. |
| format | Article |
| id | doaj-art-1bf4825501a2494291a46655226aff5a |
| institution | Kabale University |
| issn | 1687-4188 1687-4196 |
| language | English |
| publishDate | 2009-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Biomedical Imaging |
| spelling | doaj-art-1bf4825501a2494291a46655226aff5a2025-02-03T01:21:17ZengWileyInternational Journal of Biomedical Imaging1687-41881687-41962009-01-01200910.1155/2009/406854406854Elastography Method for Reconstruction of Nonlinear Breast Tissue PropertiesZ. G. Wang0Y. Liu1G. Wang2L. Z. Sun3Department of Civil and Environmental Engineering, University of Iowa, Iowa City, IA 52242, USADepartment of Biomedical Engineering, Indiana University-Purdue University Indianapolis (IUPUI), Indianapolis, IN 46202, USASchool of Biomedical Engineering and Sciences, Virginia Tech, Blacksburg, VA 24061, USADepartment of Civil and Environmental Engineering, University of California, Irvine, CA 92697, USAElastography is developed as a quantitative approach to imaging linear elastic properties of tissues to detect suspicious tumors. In this paper a nonlinear elastography method is introduced for reconstruction of complex breast tissue properties. The elastic parameters are estimated by optimally minimizing the difference between the computed forces and experimental measures. A nonlinear adjoint method is derived to calculate the gradient of the objective function, which significantly enhances the numerical efficiency and stability. Simulations are conducted on a three-dimensional heterogeneous breast phantom extracting from real imaging including fatty tissue, glandular tissue, and tumors. An exponential-form of nonlinear material model is applied. The effect of noise is taken into account. Results demonstrate that the proposed nonlinear method opens the door toward nonlinear elastography and provides guidelines for future development and clinical application in breast cancer study.http://dx.doi.org/10.1155/2009/406854 |
| spellingShingle | Z. G. Wang Y. Liu G. Wang L. Z. Sun Elastography Method for Reconstruction of Nonlinear Breast Tissue Properties International Journal of Biomedical Imaging |
| title | Elastography Method for Reconstruction of Nonlinear Breast Tissue Properties |
| title_full | Elastography Method for Reconstruction of Nonlinear Breast Tissue Properties |
| title_fullStr | Elastography Method for Reconstruction of Nonlinear Breast Tissue Properties |
| title_full_unstemmed | Elastography Method for Reconstruction of Nonlinear Breast Tissue Properties |
| title_short | Elastography Method for Reconstruction of Nonlinear Breast Tissue Properties |
| title_sort | elastography method for reconstruction of nonlinear breast tissue properties |
| url | http://dx.doi.org/10.1155/2009/406854 |
| work_keys_str_mv | AT zgwang elastographymethodforreconstructionofnonlinearbreasttissueproperties AT yliu elastographymethodforreconstructionofnonlinearbreasttissueproperties AT gwang elastographymethodforreconstructionofnonlinearbreasttissueproperties AT lzsun elastographymethodforreconstructionofnonlinearbreasttissueproperties |