Pretest Score for Predicting Microbubble Contrast Agent Use in Stress Echocardiography: A Method to Increase Efficiency in the Echo Laboratory
Background. In stress echocardiography, contrast agents are used selectively to improve endocardial border definition. Early identification of candidates may facilitate use of these agents in small and medium volume laboratories where resources are limited. Methods. We studied 15232 patients who un...
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| Format: | Article |
| Language: | English |
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Wiley
2009-01-01
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| Series: | Cardiology Research and Practice |
| Online Access: | http://dx.doi.org/10.4061/2009/308486 |
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| author | Mathieu Bernier Sahar S. Abdelmoneim Stuart Moir Robert B. McCully Patricia A. Pellikka Sharon L. Mulvagh |
| author_facet | Mathieu Bernier Sahar S. Abdelmoneim Stuart Moir Robert B. McCully Patricia A. Pellikka Sharon L. Mulvagh |
| author_sort | Mathieu Bernier |
| collection | DOAJ |
| description | Background. In stress echocardiography, contrast agents are used selectively to improve endocardial
border definition. Early identification of candidates may facilitate use of these agents in small and medium volume
laboratories where resources are limited. Methods. We studied 15232 patients who underwent stress
echocardiography. Contrast agent was used if 2 or more ventricular segments were not adequately visualized without
contrast. Logistic regression models were used to evaluate the association between individual characteristics and contrast use. An 11-point score was derived from the significant characteristics. Results. Variables associated with microbubble use were age, sex, smoking, presence of multiple risk factors, bodymass index (BMI), referral for dobutamine stress echocardiography, history of coronary artery disease, and abnormal baseline electrocardiogram. All variables except BMI were given a score of 1 if present and 0 if absent; BMI was given a score of 0 to 4 according to its value. An increased score was directly proportional to increased likelihood of contrast use. The score cutoff value to optimize sensitivity and specificity was 5. Conclusions. A pretest score can be computed from information available before imaging. It may facilitate contrast agent use through early identification of patients who are likely to benefit from improved endocardial border definition. |
| format | Article |
| id | doaj-art-1bd11b468621412c920dd2ef702fac98 |
| institution | Kabale University |
| issn | 2090-0597 |
| language | English |
| publishDate | 2009-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Cardiology Research and Practice |
| spelling | doaj-art-1bd11b468621412c920dd2ef702fac982025-02-03T06:48:28ZengWileyCardiology Research and Practice2090-05972009-01-01200910.4061/2009/308486308486Pretest Score for Predicting Microbubble Contrast Agent Use in Stress Echocardiography: A Method to Increase Efficiency in the Echo LaboratoryMathieu Bernier0Sahar S. Abdelmoneim1Stuart Moir2Robert B. McCully3Patricia A. Pellikka4Sharon L. Mulvagh5Cardiovascular Ultrasound Imaging Laboratory, Laval Hospital, QC, G1V 4G5, CanadaDivision of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota 55905, USADivision of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota 55905, USADivision of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota 55905, USADivision of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota 55905, USADivision of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota 55905, USABackground. In stress echocardiography, contrast agents are used selectively to improve endocardial border definition. Early identification of candidates may facilitate use of these agents in small and medium volume laboratories where resources are limited. Methods. We studied 15232 patients who underwent stress echocardiography. Contrast agent was used if 2 or more ventricular segments were not adequately visualized without contrast. Logistic regression models were used to evaluate the association between individual characteristics and contrast use. An 11-point score was derived from the significant characteristics. Results. Variables associated with microbubble use were age, sex, smoking, presence of multiple risk factors, bodymass index (BMI), referral for dobutamine stress echocardiography, history of coronary artery disease, and abnormal baseline electrocardiogram. All variables except BMI were given a score of 1 if present and 0 if absent; BMI was given a score of 0 to 4 according to its value. An increased score was directly proportional to increased likelihood of contrast use. The score cutoff value to optimize sensitivity and specificity was 5. Conclusions. A pretest score can be computed from information available before imaging. It may facilitate contrast agent use through early identification of patients who are likely to benefit from improved endocardial border definition.http://dx.doi.org/10.4061/2009/308486 |
| spellingShingle | Mathieu Bernier Sahar S. Abdelmoneim Stuart Moir Robert B. McCully Patricia A. Pellikka Sharon L. Mulvagh Pretest Score for Predicting Microbubble Contrast Agent Use in Stress Echocardiography: A Method to Increase Efficiency in the Echo Laboratory Cardiology Research and Practice |
| title | Pretest Score for Predicting Microbubble Contrast Agent Use in Stress Echocardiography: A Method to Increase Efficiency in the Echo Laboratory |
| title_full | Pretest Score for Predicting Microbubble Contrast Agent Use in Stress Echocardiography: A Method to Increase Efficiency in the Echo Laboratory |
| title_fullStr | Pretest Score for Predicting Microbubble Contrast Agent Use in Stress Echocardiography: A Method to Increase Efficiency in the Echo Laboratory |
| title_full_unstemmed | Pretest Score for Predicting Microbubble Contrast Agent Use in Stress Echocardiography: A Method to Increase Efficiency in the Echo Laboratory |
| title_short | Pretest Score for Predicting Microbubble Contrast Agent Use in Stress Echocardiography: A Method to Increase Efficiency in the Echo Laboratory |
| title_sort | pretest score for predicting microbubble contrast agent use in stress echocardiography a method to increase efficiency in the echo laboratory |
| url | http://dx.doi.org/10.4061/2009/308486 |
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