Exploring the Safety and Effects of COVID-19 Vaccination in Patients with Autoimmune Disease
The COVID-19 pandemic has quickly become the most significant public health phenomenon, effectively eclipsing the H1N1 and Ebola crises that came before it. It can spread rapidly and has caused the death and disability of many worldwide. Vaccines are our most effective line of defense against the r...
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Format: | Article |
Language: | English |
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HH Publisher
2022-11-01
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Series: | Progress in Microbes and Molecular Biology |
Online Access: | https://journals.hh-publisher.com/index.php/pmmb/article/view/661 |
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author | Kirttna Solai Vairavan Loh Teng-Hern Tan Jodi Woan Fei Law Priyia Pusparajah Vengadesh Letchumanan |
author_facet | Kirttna Solai Vairavan Loh Teng-Hern Tan Jodi Woan Fei Law Priyia Pusparajah Vengadesh Letchumanan |
author_sort | Kirttna Solai Vairavan |
collection | DOAJ |
description |
The COVID-19 pandemic has quickly become the most significant public health phenomenon, effectively eclipsing the H1N1 and Ebola crises that came before it. It can spread rapidly and has caused the death and disability of many worldwide. Vaccines are our most effective line of defense against the rapidly spreading and mutating virion. Still, there is significant vaccine hesitancy among those with autoimmune conditions who fear the vaccine may cause them more harm than good. This scoping review explores the safety, outcomes, and effects of COVID-19 vaccines in autoimmune patients. Online databases; Pubmed, Ovid Medline, and Scopus were used to search published literature evaluating the effectiveness and side effects of COVID-19 vaccines in patients with autoimmune conditions. The search results were limited to 4 distinct autoimmune diseases (rheumatoid arthritis, systemic lupus erythematosus, psoriasis, and myasthenia gravis). Thirty-seven studies were retrieved and assessed on the safety, effects, and outcomes of COVID-19 vaccination in patients with the chosen autoimmune conditions. Overall, the risk of flares and the development of severe side effects after vaccination was low. Most autoimmune patients showed a good antibody response to vaccination, especially after the second dose. This review provides a favorable impact of vaccination in patients with autoimmune conditions.
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format | Article |
id | doaj-art-1bb97064ba6d456986a229f6d64395bb |
institution | Kabale University |
issn | 2637-1049 |
language | English |
publishDate | 2022-11-01 |
publisher | HH Publisher |
record_format | Article |
series | Progress in Microbes and Molecular Biology |
spelling | doaj-art-1bb97064ba6d456986a229f6d64395bb2025-02-04T08:40:04ZengHH PublisherProgress in Microbes and Molecular Biology2637-10492022-11-015110.36877/pmmb.a0000277Exploring the Safety and Effects of COVID-19 Vaccination in Patients with Autoimmune DiseaseKirttna Solai VairavanLoh Teng-Hern TanJodi Woan Fei LawPriyia PusparajahVengadesh Letchumanan The COVID-19 pandemic has quickly become the most significant public health phenomenon, effectively eclipsing the H1N1 and Ebola crises that came before it. It can spread rapidly and has caused the death and disability of many worldwide. Vaccines are our most effective line of defense against the rapidly spreading and mutating virion. Still, there is significant vaccine hesitancy among those with autoimmune conditions who fear the vaccine may cause them more harm than good. This scoping review explores the safety, outcomes, and effects of COVID-19 vaccines in autoimmune patients. Online databases; Pubmed, Ovid Medline, and Scopus were used to search published literature evaluating the effectiveness and side effects of COVID-19 vaccines in patients with autoimmune conditions. The search results were limited to 4 distinct autoimmune diseases (rheumatoid arthritis, systemic lupus erythematosus, psoriasis, and myasthenia gravis). Thirty-seven studies were retrieved and assessed on the safety, effects, and outcomes of COVID-19 vaccination in patients with the chosen autoimmune conditions. Overall, the risk of flares and the development of severe side effects after vaccination was low. Most autoimmune patients showed a good antibody response to vaccination, especially after the second dose. This review provides a favorable impact of vaccination in patients with autoimmune conditions. https://journals.hh-publisher.com/index.php/pmmb/article/view/661 |
spellingShingle | Kirttna Solai Vairavan Loh Teng-Hern Tan Jodi Woan Fei Law Priyia Pusparajah Vengadesh Letchumanan Exploring the Safety and Effects of COVID-19 Vaccination in Patients with Autoimmune Disease Progress in Microbes and Molecular Biology |
title | Exploring the Safety and Effects of COVID-19 Vaccination in Patients with Autoimmune Disease |
title_full | Exploring the Safety and Effects of COVID-19 Vaccination in Patients with Autoimmune Disease |
title_fullStr | Exploring the Safety and Effects of COVID-19 Vaccination in Patients with Autoimmune Disease |
title_full_unstemmed | Exploring the Safety and Effects of COVID-19 Vaccination in Patients with Autoimmune Disease |
title_short | Exploring the Safety and Effects of COVID-19 Vaccination in Patients with Autoimmune Disease |
title_sort | exploring the safety and effects of covid 19 vaccination in patients with autoimmune disease |
url | https://journals.hh-publisher.com/index.php/pmmb/article/view/661 |
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