Exploring the Safety and Effects of COVID-19 Vaccination in Patients with Autoimmune Disease

The COVID-19 pandemic has quickly become the most significant public health phenomenon, effectively eclipsing the H1N1 and Ebola crises that came before it. It can spread rapidly and has caused the death and disability of many worldwide. Vaccines are our most effective line of defense against the r...

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Main Authors: Kirttna Solai Vairavan, Loh Teng-Hern Tan, Jodi Woan Fei Law, Priyia Pusparajah, Vengadesh Letchumanan
Format: Article
Language:English
Published: HH Publisher 2022-11-01
Series:Progress in Microbes and Molecular Biology
Online Access:https://journals.hh-publisher.com/index.php/pmmb/article/view/661
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author Kirttna Solai Vairavan
Loh Teng-Hern Tan
Jodi Woan Fei Law
Priyia Pusparajah
Vengadesh Letchumanan
author_facet Kirttna Solai Vairavan
Loh Teng-Hern Tan
Jodi Woan Fei Law
Priyia Pusparajah
Vengadesh Letchumanan
author_sort Kirttna Solai Vairavan
collection DOAJ
description The COVID-19 pandemic has quickly become the most significant public health phenomenon, effectively eclipsing the H1N1 and Ebola crises that came before it. It can spread rapidly and has caused the death and disability of many worldwide. Vaccines are our most effective line of defense against the rapidly spreading and mutating virion. Still, there is significant vaccine hesitancy among those with autoimmune conditions who fear the vaccine may cause them more harm than good. This scoping review explores the safety, outcomes, and effects of COVID-19 vaccines in autoimmune patients. Online databases; Pubmed, Ovid Medline, and Scopus were used to search published literature evaluating the effectiveness and side effects of COVID-19 vaccines in patients with autoimmune conditions. The search results were limited to 4 distinct autoimmune diseases (rheumatoid arthritis, systemic lupus erythematosus, psoriasis, and myasthenia gravis). Thirty-seven studies were retrieved and assessed on the safety, effects, and outcomes of COVID-19 vaccination in patients with the chosen autoimmune conditions. Overall, the risk of flares and the development of severe side effects after vaccination was low. Most autoimmune patients showed a good antibody response to vaccination, especially after the second dose. This review provides a favorable impact of vaccination in patients with autoimmune conditions.
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series Progress in Microbes and Molecular Biology
spelling doaj-art-1bb97064ba6d456986a229f6d64395bb2025-02-04T08:40:04ZengHH PublisherProgress in Microbes and Molecular Biology2637-10492022-11-015110.36877/pmmb.a0000277Exploring the Safety and Effects of COVID-19 Vaccination in Patients with Autoimmune DiseaseKirttna Solai VairavanLoh Teng-Hern TanJodi Woan Fei LawPriyia PusparajahVengadesh Letchumanan The COVID-19 pandemic has quickly become the most significant public health phenomenon, effectively eclipsing the H1N1 and Ebola crises that came before it. It can spread rapidly and has caused the death and disability of many worldwide. Vaccines are our most effective line of defense against the rapidly spreading and mutating virion. Still, there is significant vaccine hesitancy among those with autoimmune conditions who fear the vaccine may cause them more harm than good. This scoping review explores the safety, outcomes, and effects of COVID-19 vaccines in autoimmune patients. Online databases; Pubmed, Ovid Medline, and Scopus were used to search published literature evaluating the effectiveness and side effects of COVID-19 vaccines in patients with autoimmune conditions. The search results were limited to 4 distinct autoimmune diseases (rheumatoid arthritis, systemic lupus erythematosus, psoriasis, and myasthenia gravis). Thirty-seven studies were retrieved and assessed on the safety, effects, and outcomes of COVID-19 vaccination in patients with the chosen autoimmune conditions. Overall, the risk of flares and the development of severe side effects after vaccination was low. Most autoimmune patients showed a good antibody response to vaccination, especially after the second dose. This review provides a favorable impact of vaccination in patients with autoimmune conditions. https://journals.hh-publisher.com/index.php/pmmb/article/view/661
spellingShingle Kirttna Solai Vairavan
Loh Teng-Hern Tan
Jodi Woan Fei Law
Priyia Pusparajah
Vengadesh Letchumanan
Exploring the Safety and Effects of COVID-19 Vaccination in Patients with Autoimmune Disease
Progress in Microbes and Molecular Biology
title Exploring the Safety and Effects of COVID-19 Vaccination in Patients with Autoimmune Disease
title_full Exploring the Safety and Effects of COVID-19 Vaccination in Patients with Autoimmune Disease
title_fullStr Exploring the Safety and Effects of COVID-19 Vaccination in Patients with Autoimmune Disease
title_full_unstemmed Exploring the Safety and Effects of COVID-19 Vaccination in Patients with Autoimmune Disease
title_short Exploring the Safety and Effects of COVID-19 Vaccination in Patients with Autoimmune Disease
title_sort exploring the safety and effects of covid 19 vaccination in patients with autoimmune disease
url https://journals.hh-publisher.com/index.php/pmmb/article/view/661
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