Age-Related Changes of the Ocular Surface: A Hospital Setting-Based Retrospective Study

Purpose. To investigate the effects of age on the prevalence of ocular surface diseases (OSD), adherence to treatment, and recovery rates. Patients and Methods. Retrospective analysis of 3000 clinical records from a first-level general ophthalmology clinic. Patients with OSD were prospectively submi...

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Main Authors: Laura Ottobelli, Paolo Fogagnolo, Marta Guerini, Luca Rossetti
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2014/532378
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author Laura Ottobelli
Paolo Fogagnolo
Marta Guerini
Luca Rossetti
author_facet Laura Ottobelli
Paolo Fogagnolo
Marta Guerini
Luca Rossetti
author_sort Laura Ottobelli
collection DOAJ
description Purpose. To investigate the effects of age on the prevalence of ocular surface diseases (OSD), adherence to treatment, and recovery rates. Patients and Methods. Retrospective analysis of 3000 clinical records from a first-level general ophthalmology clinic. Patients with OSD were prospectively submitted a questionnaire to assess compliance and recovery rates. Results. OSD prevalence was 10.3%. Patients with OSD were significantly older than patients without it: 67.5±20.3 versus 57.0±22.0 years (P=0.036). No significant difference in season distribution was shown. Dry eye disease (DED) represented 58% of OSD; its prevalence increased with age until 80 years old and suddenly decreased thereafter. Asymptomatic DED was 37%. Adherence to treatment in OSD was very high (94%); recovery rates were lower in patients aged 21–40 and 61–80 (resp., 65.5% and 77.8%) and this was associated with higher OSDI scores. Tear substitutes represented 50% of all prescribed medications; their use increased with age. Discussion. In a “real-life” low-tech setting, OSD showed a prevalence of 10.3%. DED was the most prevalent disease, and it was asymptomatic in more than 1/3 of cases.
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institution Kabale University
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spelling doaj-art-1b9a430a4d34459894a9d0f3608de6962025-02-03T01:03:27ZengWileyJournal of Ophthalmology2090-004X2090-00582014-01-01201410.1155/2014/532378532378Age-Related Changes of the Ocular Surface: A Hospital Setting-Based Retrospective StudyLaura Ottobelli0Paolo Fogagnolo1Marta Guerini2Luca Rossetti3Eye Clinic, Dipartimento di Scienze della Salute, San Paolo Hospital, University of Milan, 20142 Milan, ItalyEye Clinic, Dipartimento di Scienze della Salute, San Paolo Hospital, University of Milan, 20142 Milan, ItalyEye Clinic, Dipartimento di Scienze della Salute, San Paolo Hospital, University of Milan, 20142 Milan, ItalyEye Clinic, Dipartimento di Scienze della Salute, San Paolo Hospital, University of Milan, 20142 Milan, ItalyPurpose. To investigate the effects of age on the prevalence of ocular surface diseases (OSD), adherence to treatment, and recovery rates. Patients and Methods. Retrospective analysis of 3000 clinical records from a first-level general ophthalmology clinic. Patients with OSD were prospectively submitted a questionnaire to assess compliance and recovery rates. Results. OSD prevalence was 10.3%. Patients with OSD were significantly older than patients without it: 67.5±20.3 versus 57.0±22.0 years (P=0.036). No significant difference in season distribution was shown. Dry eye disease (DED) represented 58% of OSD; its prevalence increased with age until 80 years old and suddenly decreased thereafter. Asymptomatic DED was 37%. Adherence to treatment in OSD was very high (94%); recovery rates were lower in patients aged 21–40 and 61–80 (resp., 65.5% and 77.8%) and this was associated with higher OSDI scores. Tear substitutes represented 50% of all prescribed medications; their use increased with age. Discussion. In a “real-life” low-tech setting, OSD showed a prevalence of 10.3%. DED was the most prevalent disease, and it was asymptomatic in more than 1/3 of cases.http://dx.doi.org/10.1155/2014/532378
spellingShingle Laura Ottobelli
Paolo Fogagnolo
Marta Guerini
Luca Rossetti
Age-Related Changes of the Ocular Surface: A Hospital Setting-Based Retrospective Study
Journal of Ophthalmology
title Age-Related Changes of the Ocular Surface: A Hospital Setting-Based Retrospective Study
title_full Age-Related Changes of the Ocular Surface: A Hospital Setting-Based Retrospective Study
title_fullStr Age-Related Changes of the Ocular Surface: A Hospital Setting-Based Retrospective Study
title_full_unstemmed Age-Related Changes of the Ocular Surface: A Hospital Setting-Based Retrospective Study
title_short Age-Related Changes of the Ocular Surface: A Hospital Setting-Based Retrospective Study
title_sort age related changes of the ocular surface a hospital setting based retrospective study
url http://dx.doi.org/10.1155/2014/532378
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AT martaguerini agerelatedchangesoftheocularsurfaceahospitalsettingbasedretrospectivestudy
AT lucarossetti agerelatedchangesoftheocularsurfaceahospitalsettingbasedretrospectivestudy