Preimplantation Genetic Screening: An Effective Testing for Infertile and Repeated Miscarriage Patients?
Aneuploidy in pregnancy is known to increase with advanced maternal age (AMA) and associate with repeated implantation failure (RIF), and repeated miscarriage (RM). Preimplantation genetic screening (PGS) has been introduced into clinical practice, screening, and eliminating aneuploidy embryos, whic...
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| Format: | Article |
| Language: | English |
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Wiley
2010-01-01
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| Series: | Obstetrics and Gynecology International |
| Online Access: | http://dx.doi.org/10.1155/2010/120130 |
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| author | Ning Wang Ying-Ming Zheng Lei Li Fan Jin |
| author_facet | Ning Wang Ying-Ming Zheng Lei Li Fan Jin |
| author_sort | Ning Wang |
| collection | DOAJ |
| description | Aneuploidy in pregnancy is known to increase with advanced maternal age (AMA) and associate with repeated implantation failure (RIF), and repeated miscarriage (RM). Preimplantation genetic screening (PGS) has been introduced into clinical practice, screening, and eliminating aneuploidy embryos, which can improve the chance of conceptions for infertility cases with poor prognosis. These patients are a good target group to assess the possible benefit of aneuploidy screening. Although practiced widely throughout the world, there still exist some doubts about the efficacy of this technique. Recent randomized trials were not as desirable as we expected, suggesting that PGS needs to be reconsidered. The aim of this review is to discuss the efficacy of PGS. |
| format | Article |
| id | doaj-art-1b8dd1172899420398aba147a5c83adc |
| institution | Kabale University |
| issn | 1687-9589 1687-9597 |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Obstetrics and Gynecology International |
| spelling | doaj-art-1b8dd1172899420398aba147a5c83adc2025-02-03T06:11:44ZengWileyObstetrics and Gynecology International1687-95891687-95972010-01-01201010.1155/2010/120130120130Preimplantation Genetic Screening: An Effective Testing for Infertile and Repeated Miscarriage Patients?Ning Wang0Ying-Ming Zheng1Lei Li2Fan Jin3Department of Reproductive Endocrinology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou 310006, ChinaDepartment of Reproductive Endocrinology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou 310006, ChinaDepartment of Reproductive Endocrinology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou 310006, ChinaDepartment of Reproductive Endocrinology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou 310006, ChinaAneuploidy in pregnancy is known to increase with advanced maternal age (AMA) and associate with repeated implantation failure (RIF), and repeated miscarriage (RM). Preimplantation genetic screening (PGS) has been introduced into clinical practice, screening, and eliminating aneuploidy embryos, which can improve the chance of conceptions for infertility cases with poor prognosis. These patients are a good target group to assess the possible benefit of aneuploidy screening. Although practiced widely throughout the world, there still exist some doubts about the efficacy of this technique. Recent randomized trials were not as desirable as we expected, suggesting that PGS needs to be reconsidered. The aim of this review is to discuss the efficacy of PGS.http://dx.doi.org/10.1155/2010/120130 |
| spellingShingle | Ning Wang Ying-Ming Zheng Lei Li Fan Jin Preimplantation Genetic Screening: An Effective Testing for Infertile and Repeated Miscarriage Patients? Obstetrics and Gynecology International |
| title | Preimplantation Genetic Screening: An Effective Testing for Infertile and Repeated Miscarriage Patients? |
| title_full | Preimplantation Genetic Screening: An Effective Testing for Infertile and Repeated Miscarriage Patients? |
| title_fullStr | Preimplantation Genetic Screening: An Effective Testing for Infertile and Repeated Miscarriage Patients? |
| title_full_unstemmed | Preimplantation Genetic Screening: An Effective Testing for Infertile and Repeated Miscarriage Patients? |
| title_short | Preimplantation Genetic Screening: An Effective Testing for Infertile and Repeated Miscarriage Patients? |
| title_sort | preimplantation genetic screening an effective testing for infertile and repeated miscarriage patients |
| url | http://dx.doi.org/10.1155/2010/120130 |
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