Serial cerebrospinal fluid concentrations of high mobility group box 1 in bacterial meningitis: a retrospective cohort study

Serial cerebrospinal fluid concentrations of high mobility group box 1 in bacterial meningitis: a retrospective cohort study

Abstract Background Bacterial meningitis (BM) is a life-threatening central nervous system infection with potential for severe neurological sequelae. High mobility group box 1 (HMGB1) is known as a late inflammatory mediator associated with lethal pathology. This study aims to investigate the serial...

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Main Authors: Takeshi Matsushige, Hirofumi Inoue, Madoka Hoshide, Fumitaka Kohno, Hikaru Kobayashi, Kiyoshi Ichihara, Takashi Ichiyama, Shunji Hasegawa
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Infectious Diseases
Subjects:
Bacterial meningitis
Cerebrospinal fluid
High mobility group box 1
Cytokine
Prognosis
Online Access:https://doi.org/10.1186/s12879-025-10476-7
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