Osteoporosis Self-Assessment Tool Performance in a Large Sample of Postmenopausal Women of Mendoza, Argentina

The Osteoporosis Self-assessment Tool (OST) is a clinical instrument designed to select patients at risk of osteoporosis, who would benefit from a bone mineral density measurement. The OST only takes into account the age and weight of the subject. It was developed for Asian women and later validated...

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Main Author: Fernando D. Saraví
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Journal of Osteoporosis
Online Access:http://dx.doi.org/10.1155/2013/150154
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author Fernando D. Saraví
author_facet Fernando D. Saraví
author_sort Fernando D. Saraví
collection DOAJ
description The Osteoporosis Self-assessment Tool (OST) is a clinical instrument designed to select patients at risk of osteoporosis, who would benefit from a bone mineral density measurement. The OST only takes into account the age and weight of the subject. It was developed for Asian women and later validated for European and North American white women. The performance of the OST in a sample of 4343 women from Greater Mendoza, a large metropolitan area of Argentina, was assessed. Dual X-ray absorptiometry (DXA) scans of lumbar spine and hip were obtained. Patients were classified as either osteoporotic (N=1830) or nonosteoporotic (n=2513) according to their lowest T-score at any site. Osteoporotic patients had lower OST scores (P<0.0001). A receiver operating characteristic (ROC) curve showed an area under the curve of 71% (P<0.0001), with a sensitivity of 83.7% and a specificity of 44% for a cut-off value of 2. Positive predictive value was 52% and negative predictive value was 79%. The odds ratio for the diagnosis of osteoporosis was 4.06 (CI95 3.51 to 4.71; P<0.0001). It is concluded that the OST is useful for selecting postmenopausal women for DXA testing in the studied population.
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spelling doaj-art-1b69bf5394c446dea08e15e19a16d0ec2025-02-03T06:11:44ZengWileyJournal of Osteoporosis2090-80592042-00642013-01-01201310.1155/2013/150154150154Osteoporosis Self-Assessment Tool Performance in a Large Sample of Postmenopausal Women of Mendoza, ArgentinaFernando D. Saraví0Bone Densitometry Unit, Nuclear Medicine School, Garibaldi 405, 5500 Mendoza, ArgentinaThe Osteoporosis Self-assessment Tool (OST) is a clinical instrument designed to select patients at risk of osteoporosis, who would benefit from a bone mineral density measurement. The OST only takes into account the age and weight of the subject. It was developed for Asian women and later validated for European and North American white women. The performance of the OST in a sample of 4343 women from Greater Mendoza, a large metropolitan area of Argentina, was assessed. Dual X-ray absorptiometry (DXA) scans of lumbar spine and hip were obtained. Patients were classified as either osteoporotic (N=1830) or nonosteoporotic (n=2513) according to their lowest T-score at any site. Osteoporotic patients had lower OST scores (P<0.0001). A receiver operating characteristic (ROC) curve showed an area under the curve of 71% (P<0.0001), with a sensitivity of 83.7% and a specificity of 44% for a cut-off value of 2. Positive predictive value was 52% and negative predictive value was 79%. The odds ratio for the diagnosis of osteoporosis was 4.06 (CI95 3.51 to 4.71; P<0.0001). It is concluded that the OST is useful for selecting postmenopausal women for DXA testing in the studied population.http://dx.doi.org/10.1155/2013/150154
spellingShingle Fernando D. Saraví
Osteoporosis Self-Assessment Tool Performance in a Large Sample of Postmenopausal Women of Mendoza, Argentina
Journal of Osteoporosis
title Osteoporosis Self-Assessment Tool Performance in a Large Sample of Postmenopausal Women of Mendoza, Argentina
title_full Osteoporosis Self-Assessment Tool Performance in a Large Sample of Postmenopausal Women of Mendoza, Argentina
title_fullStr Osteoporosis Self-Assessment Tool Performance in a Large Sample of Postmenopausal Women of Mendoza, Argentina
title_full_unstemmed Osteoporosis Self-Assessment Tool Performance in a Large Sample of Postmenopausal Women of Mendoza, Argentina
title_short Osteoporosis Self-Assessment Tool Performance in a Large Sample of Postmenopausal Women of Mendoza, Argentina
title_sort osteoporosis self assessment tool performance in a large sample of postmenopausal women of mendoza argentina
url http://dx.doi.org/10.1155/2013/150154
work_keys_str_mv AT fernandodsaravi osteoporosisselfassessmenttoolperformanceinalargesampleofpostmenopausalwomenofmendozaargentina