Gastrointestinal Stromal Tumours: Etiology, Pathology and Clinical Management
Investigation of the regulation of cell growth, differentiation and death by signalling pathways has led to a greater understanding of how alterations in these pathways play a critical role in the development of some cancers, and has opened new opportunities for their treatment. In the present revie...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2004-01-01
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| Series: | Canadian Journal of Gastroenterology |
| Online Access: | http://dx.doi.org/10.1155/2004/238037 |
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| _version_ | 1832567021099810816 |
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| author | Martin E Blackstein Pierre Dubé Jonathan A Fletcher Oliver R Keller Margaret Knowling Richard Létourneau Donald Morris Robert Riddell Stewart Rorke Carol J Swallow Canadian Advisory Committee on GIST |
| author_facet | Martin E Blackstein Pierre Dubé Jonathan A Fletcher Oliver R Keller Margaret Knowling Richard Létourneau Donald Morris Robert Riddell Stewart Rorke Carol J Swallow Canadian Advisory Committee on GIST |
| author_sort | Martin E Blackstein |
| collection | DOAJ |
| description | Investigation of the regulation of cell growth, differentiation and
death by signalling pathways has led to a greater understanding of
how alterations in these pathways play a critical role in the development
of some cancers, and has opened new opportunities for their
treatment. In the present review, results with the prototype drug of
this class, imatinib (Gleevec, Glivec [formerly STI571]; Novartis,
Switzerland), in metastatic gastrointestinal stromal tumours are presented.
The present review originated from a conference of the
authors held in Montreal, Quebec in June 2003, under the sponsorship
of Novartis. |
| format | Article |
| id | doaj-art-1b0ec018271f48a59964ca2614839313 |
| institution | Kabale University |
| issn | 0835-7900 |
| language | English |
| publishDate | 2004-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Gastroenterology |
| spelling | doaj-art-1b0ec018271f48a59964ca26148393132025-02-03T01:02:27ZengWileyCanadian Journal of Gastroenterology0835-79002004-01-0118Suppl B3B8B10.1155/2004/238037Gastrointestinal Stromal Tumours: Etiology, Pathology and Clinical ManagementMartin E Blackstein0Pierre Dubé1Jonathan A Fletcher2Oliver R Keller3Margaret Knowling4Richard Létourneau5Donald Morris6Robert Riddell7Stewart Rorke8Carol J Swallow9Canadian Advisory Committee on GIST10Mount Sinai Hospital, Toronto, Ontario, CanadaCentre Hospitalier Maisonneuve-Rosemont, Montreal, Quebec, CanadaBrigham and Women’s Hospital, Boston, Massachusetts, USAOttawa Regional Cancer Centre, Ottawa, Ontario, CanadaBritish Columbia Cancer Agency – Vancouver Cancer Clinic, Vancouver, British Columbia, CanadaCentre Hospitalier de l’Université de Montréal, Montreal, Quebec, CanadaTom Baker Cancer Centre, Calgary, Alberta, CanadaMount Sinai Hospital, Toronto, Ontario, CanadaDr H Bliss Murphy Cancer Centre, St John’s, Newfoundland, CanadaMount Sinai Hospital, Toronto, Ontario, CanadaMount Sinai Hospital, Toronto, Ontario, CanadaInvestigation of the regulation of cell growth, differentiation and death by signalling pathways has led to a greater understanding of how alterations in these pathways play a critical role in the development of some cancers, and has opened new opportunities for their treatment. In the present review, results with the prototype drug of this class, imatinib (Gleevec, Glivec [formerly STI571]; Novartis, Switzerland), in metastatic gastrointestinal stromal tumours are presented. The present review originated from a conference of the authors held in Montreal, Quebec in June 2003, under the sponsorship of Novartis.http://dx.doi.org/10.1155/2004/238037 |
| spellingShingle | Martin E Blackstein Pierre Dubé Jonathan A Fletcher Oliver R Keller Margaret Knowling Richard Létourneau Donald Morris Robert Riddell Stewart Rorke Carol J Swallow Canadian Advisory Committee on GIST Gastrointestinal Stromal Tumours: Etiology, Pathology and Clinical Management Canadian Journal of Gastroenterology |
| title | Gastrointestinal Stromal Tumours: Etiology, Pathology and Clinical Management |
| title_full | Gastrointestinal Stromal Tumours: Etiology, Pathology and Clinical Management |
| title_fullStr | Gastrointestinal Stromal Tumours: Etiology, Pathology and Clinical Management |
| title_full_unstemmed | Gastrointestinal Stromal Tumours: Etiology, Pathology and Clinical Management |
| title_short | Gastrointestinal Stromal Tumours: Etiology, Pathology and Clinical Management |
| title_sort | gastrointestinal stromal tumours etiology pathology and clinical management |
| url | http://dx.doi.org/10.1155/2004/238037 |
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