Gastrointestinal Stromal Tumours: Etiology, Pathology and Clinical Management
Investigation of the regulation of cell growth, differentiation and death by signalling pathways has led to a greater understanding of how alterations in these pathways play a critical role in the development of some cancers, and has opened new opportunities for their treatment. In the present revie...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2004-01-01
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| Series: | Canadian Journal of Gastroenterology |
| Online Access: | http://dx.doi.org/10.1155/2004/238037 |
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| Summary: | Investigation of the regulation of cell growth, differentiation and
death by signalling pathways has led to a greater understanding of
how alterations in these pathways play a critical role in the development
of some cancers, and has opened new opportunities for their
treatment. In the present review, results with the prototype drug of
this class, imatinib (Gleevec, Glivec [formerly STI571]; Novartis,
Switzerland), in metastatic gastrointestinal stromal tumours are presented.
The present review originated from a conference of the
authors held in Montreal, Quebec in June 2003, under the sponsorship
of Novartis. |
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| ISSN: | 0835-7900 |