Confusional State in HaNDL Syndrome: Case Report and Literature Review
The syndrome of transient headache and neurologic deficits with cerebrospinal fluid lymphocytosis (HaNDL syndrome) is a self-limited condition. Confusional states are uncommonly reported as a clinical manifestation of this syndrome. Here, I report a 76-year-old female who presented with headache, co...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Case Reports in Neurological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2013/317685 |
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| _version_ | 1832556045582467072 |
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| author | Sarah Nelson |
| author_facet | Sarah Nelson |
| author_sort | Sarah Nelson |
| collection | DOAJ |
| description | The syndrome of transient headache and neurologic deficits with cerebrospinal fluid lymphocytosis (HaNDL syndrome) is a self-limited condition. Confusional states are uncommonly reported as a clinical manifestation of this syndrome. Here, I report a 76-year-old female who presented with headache, confusion, and agitation with a mild CSF lymphocytosis. Other workup to determine the cause of her altered mental status was otherwise negative. The literature available in the English language on HaNDL syndrome is reviewed, including its history, pathophysiology, possible associations with migraine and stroke, and previously reported cases of confusional states in this syndrome. While HaNDL syndrome has been a described entity since the 1980s, its pathophysiology has yet to be clearly defined. |
| format | Article |
| id | doaj-art-1aea6162626e4182a327df052ac99fab |
| institution | Kabale University |
| issn | 2090-6668 2090-6676 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Neurological Medicine |
| spelling | doaj-art-1aea6162626e4182a327df052ac99fab2025-02-03T05:46:28ZengWileyCase Reports in Neurological Medicine2090-66682090-66762013-01-01201310.1155/2013/317685317685Confusional State in HaNDL Syndrome: Case Report and Literature ReviewSarah Nelson0Tufts Medical Center, 800 Washington Street No. 314, Boston, MA 02111, USAThe syndrome of transient headache and neurologic deficits with cerebrospinal fluid lymphocytosis (HaNDL syndrome) is a self-limited condition. Confusional states are uncommonly reported as a clinical manifestation of this syndrome. Here, I report a 76-year-old female who presented with headache, confusion, and agitation with a mild CSF lymphocytosis. Other workup to determine the cause of her altered mental status was otherwise negative. The literature available in the English language on HaNDL syndrome is reviewed, including its history, pathophysiology, possible associations with migraine and stroke, and previously reported cases of confusional states in this syndrome. While HaNDL syndrome has been a described entity since the 1980s, its pathophysiology has yet to be clearly defined.http://dx.doi.org/10.1155/2013/317685 |
| spellingShingle | Sarah Nelson Confusional State in HaNDL Syndrome: Case Report and Literature Review Case Reports in Neurological Medicine |
| title | Confusional State in HaNDL Syndrome: Case Report and Literature Review |
| title_full | Confusional State in HaNDL Syndrome: Case Report and Literature Review |
| title_fullStr | Confusional State in HaNDL Syndrome: Case Report and Literature Review |
| title_full_unstemmed | Confusional State in HaNDL Syndrome: Case Report and Literature Review |
| title_short | Confusional State in HaNDL Syndrome: Case Report and Literature Review |
| title_sort | confusional state in handl syndrome case report and literature review |
| url | http://dx.doi.org/10.1155/2013/317685 |
| work_keys_str_mv | AT sarahnelson confusionalstateinhandlsyndromecasereportandliteraturereview |