Leiomyosarcoma of Pulmonary Vein Presenting as Left Atrial Mass: An Outline of Management Principles
Leiomyosarcoma of the pulmonary vein is rare and has poor prognosis. Its clinical features are nonspecific and mimic benign conditions. Early diagnosis is challenging. Most cases have been diagnosed only at autopsy or on postoperative histology specimens. Treatment is essentially palliative complete...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Case Reports in Cardiology |
| Online Access: | http://dx.doi.org/10.1155/2012/396319 |
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| author | Philemon Gukop Guido Frassetto Georgios Karapanagiotidis Venkatachalam Chandrasekaran |
| author_facet | Philemon Gukop Guido Frassetto Georgios Karapanagiotidis Venkatachalam Chandrasekaran |
| author_sort | Philemon Gukop |
| collection | DOAJ |
| description | Leiomyosarcoma of the pulmonary vein is rare and has poor prognosis. Its clinical features are nonspecific and mimic benign conditions. Early diagnosis is challenging. Most cases have been diagnosed only at autopsy or on postoperative histology specimens. Treatment is essentially palliative complete surgical excision. We outline the principles of management with the case of a 39-year-old man with leiomyosarcoma of the left pulmonary veins extending into the left atrium. Extensive investigation to achieve early diagnosis and determine extent of disease is essential. Frozen section guided adequate excision of all cardiac tumours and resection of involved lung tissue achieve local disease control. Adjuvant chemoradiotherapy has been shown to enhance survival. |
| format | Article |
| id | doaj-art-1ae6dcea9cca4fd8a928b51569158bae |
| institution | Kabale University |
| issn | 2090-6404 2090-6412 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Cardiology |
| spelling | doaj-art-1ae6dcea9cca4fd8a928b51569158bae2025-02-03T06:14:16ZengWileyCase Reports in Cardiology2090-64042090-64122012-01-01201210.1155/2012/396319396319Leiomyosarcoma of Pulmonary Vein Presenting as Left Atrial Mass: An Outline of Management PrinciplesPhilemon Gukop0Guido Frassetto1Georgios Karapanagiotidis2Venkatachalam Chandrasekaran3Department of Cardiothoracic Surgery, St George’s Hospital, London SW17 0QT, UKDepartment of Cardiothoracic Surgery, St George’s Hospital, London SW17 0QT, UKDepartment of Cardiothoracic Surgery, St George’s Hospital, London SW17 0QT, UKDepartment of Cardiothoracic Surgery, St George’s Hospital, London SW17 0QT, UKLeiomyosarcoma of the pulmonary vein is rare and has poor prognosis. Its clinical features are nonspecific and mimic benign conditions. Early diagnosis is challenging. Most cases have been diagnosed only at autopsy or on postoperative histology specimens. Treatment is essentially palliative complete surgical excision. We outline the principles of management with the case of a 39-year-old man with leiomyosarcoma of the left pulmonary veins extending into the left atrium. Extensive investigation to achieve early diagnosis and determine extent of disease is essential. Frozen section guided adequate excision of all cardiac tumours and resection of involved lung tissue achieve local disease control. Adjuvant chemoradiotherapy has been shown to enhance survival.http://dx.doi.org/10.1155/2012/396319 |
| spellingShingle | Philemon Gukop Guido Frassetto Georgios Karapanagiotidis Venkatachalam Chandrasekaran Leiomyosarcoma of Pulmonary Vein Presenting as Left Atrial Mass: An Outline of Management Principles Case Reports in Cardiology |
| title | Leiomyosarcoma of Pulmonary Vein Presenting as Left Atrial Mass: An Outline of Management Principles |
| title_full | Leiomyosarcoma of Pulmonary Vein Presenting as Left Atrial Mass: An Outline of Management Principles |
| title_fullStr | Leiomyosarcoma of Pulmonary Vein Presenting as Left Atrial Mass: An Outline of Management Principles |
| title_full_unstemmed | Leiomyosarcoma of Pulmonary Vein Presenting as Left Atrial Mass: An Outline of Management Principles |
| title_short | Leiomyosarcoma of Pulmonary Vein Presenting as Left Atrial Mass: An Outline of Management Principles |
| title_sort | leiomyosarcoma of pulmonary vein presenting as left atrial mass an outline of management principles |
| url | http://dx.doi.org/10.1155/2012/396319 |
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