A Case of Primary Hyperparathyroidism due to Intrathyroidal Parathyroid Cyst
Parathyroid cysts constitute 0.08–3.41% of all parathyroid masses. Intrathyroidal parathyroid cysts, however, are rare conditions with only a few cases being reported. Most of the parathyroid cysts are found to be nonfunctional and functional cysts are generally thought to be due to cystic degenera...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Case Reports in Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2014/213283 |
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| author | Yavuz Yalcin Turkan Mete Recep Aktimur Gultekin Ozan Kucuk Gulhan Duman Aysu Basak Ozbalci Omer Alici |
| author_facet | Yavuz Yalcin Turkan Mete Recep Aktimur Gultekin Ozan Kucuk Gulhan Duman Aysu Basak Ozbalci Omer Alici |
| author_sort | Yavuz Yalcin |
| collection | DOAJ |
| description | Parathyroid cysts constitute 0.08–3.41% of all parathyroid masses. Intrathyroidal parathyroid cysts, however, are rare conditions with only a few cases being reported. Most of the parathyroid cysts are found to be nonfunctional and functional cysts are generally thought to be due to cystic degeneration of parathyroid adenomas. A cystic, smooth contoured lesion of 24 × 19 × 16 mm was observed in left thyroid lobe of a 76-year-old woman during ultrasonography which was performed as routine workup for primary hyperparathyroidism. It was defined as a cystic thyroid nodule at first. Tc99m sestamibi scintigraphy was performed to see any parathyroid lesions, but no radioactive uptake was observed. Intact parathormone (iPTH) level was found to be >600 pg/mL in cyst aspiration fluid. Left lobectomy was performed, with a diagnosis of primary hyperparathyroidism due to functional parathyroid cyst. Serum iPTH level was decreased >50% postoperatively and histopathological evaluation was consistent with an encapsulated parathyroid adenoma with a cystic center. Parathyroid cysts are among rare causes of primary hyperparathyroidism. Diagnosis is made by markedly increased iPTH level in cyst fluid and observation of parathyroid epithelium lining the cyst wall. |
| format | Article |
| id | doaj-art-1adb7a5de61c4be69c1de5fae3816435 |
| institution | Kabale University |
| issn | 2090-6501 2090-651X |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Endocrinology |
| spelling | doaj-art-1adb7a5de61c4be69c1de5fae38164352025-02-03T01:09:10ZengWileyCase Reports in Endocrinology2090-65012090-651X2014-01-01201410.1155/2014/213283213283A Case of Primary Hyperparathyroidism due to Intrathyroidal Parathyroid CystYavuz Yalcin0Turkan Mete1Recep Aktimur2Gultekin Ozan Kucuk3Gulhan Duman4Aysu Basak Ozbalci5Omer Alici6Department of Endocrinology and Metabolism, Ordu Training and Research Hospital, Ministry of Health, Ordu, TurkeyDepartment of Endocrinology and Metabolism, Samsun Training and Research Hospital, Ministry of Health, Samsun, TurkeyDepartment of General Surgery, Samsun Training and Research Hospital, Ministry of Health, Samsun, TurkeyDepartment of General Surgery, Samsun Training and Research Hospital, Ministry of Health, Samsun, TurkeyDepartment of Endocrinology and Metabolism, Samsun Training and Research Hospital, Ministry of Health, Samsun, TurkeyDepartment of Radiology, Samsun Training and Research Hospital, Ministry of Health, Samsun, TurkeyDepartment of Pathology, Samsun Training and Research Hospital, Ministry of Health, Samsun, TurkeyParathyroid cysts constitute 0.08–3.41% of all parathyroid masses. Intrathyroidal parathyroid cysts, however, are rare conditions with only a few cases being reported. Most of the parathyroid cysts are found to be nonfunctional and functional cysts are generally thought to be due to cystic degeneration of parathyroid adenomas. A cystic, smooth contoured lesion of 24 × 19 × 16 mm was observed in left thyroid lobe of a 76-year-old woman during ultrasonography which was performed as routine workup for primary hyperparathyroidism. It was defined as a cystic thyroid nodule at first. Tc99m sestamibi scintigraphy was performed to see any parathyroid lesions, but no radioactive uptake was observed. Intact parathormone (iPTH) level was found to be >600 pg/mL in cyst aspiration fluid. Left lobectomy was performed, with a diagnosis of primary hyperparathyroidism due to functional parathyroid cyst. Serum iPTH level was decreased >50% postoperatively and histopathological evaluation was consistent with an encapsulated parathyroid adenoma with a cystic center. Parathyroid cysts are among rare causes of primary hyperparathyroidism. Diagnosis is made by markedly increased iPTH level in cyst fluid and observation of parathyroid epithelium lining the cyst wall.http://dx.doi.org/10.1155/2014/213283 |
| spellingShingle | Yavuz Yalcin Turkan Mete Recep Aktimur Gultekin Ozan Kucuk Gulhan Duman Aysu Basak Ozbalci Omer Alici A Case of Primary Hyperparathyroidism due to Intrathyroidal Parathyroid Cyst Case Reports in Endocrinology |
| title | A Case of Primary Hyperparathyroidism due to Intrathyroidal Parathyroid Cyst |
| title_full | A Case of Primary Hyperparathyroidism due to Intrathyroidal Parathyroid Cyst |
| title_fullStr | A Case of Primary Hyperparathyroidism due to Intrathyroidal Parathyroid Cyst |
| title_full_unstemmed | A Case of Primary Hyperparathyroidism due to Intrathyroidal Parathyroid Cyst |
| title_short | A Case of Primary Hyperparathyroidism due to Intrathyroidal Parathyroid Cyst |
| title_sort | case of primary hyperparathyroidism due to intrathyroidal parathyroid cyst |
| url | http://dx.doi.org/10.1155/2014/213283 |
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