Circulating CD4+CD28null T Cells May Increase the Risk of an Atherosclerotic Vascular Event Shortly after Kidney Transplantation

Circulating CD4+CD28null T Cells May Increase the Risk of an Atherosclerotic Vascular Event Shortly after Kidney Transplantation

Proinflammatory CD4+ T cells without the costimulatory molecule CD28 (CD4+CD28null T cells) are expanded in patients with end-stage renal disease (ESRD) and associated with atherosclerotic vascular events (AVE). In a prospective study, the number of circulating CD4+CD28null T cells was established i...

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Bibliographic Details
Main Authors: Michiel G. H. Betjes, Willem Weimar, Nicolle H. R. Litjens
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Journal of Transplantation
Online Access:http://dx.doi.org/10.1155/2013/841430
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