Role of the IL-6 Gene in the Etiopathogenesis of Idiopathic Scoliosis

Role of the IL-6 Gene in the Etiopathogenesis of Idiopathic Scoliosis

Scoliotic human nuclei pulposi can respond to exogenous proinflammatory stimuli by secreting increased amounts of interleukin-6 (IL-6). The G/C polymorphism of the promoter region of IL-6 gene influences levels and functional activity of the IL-6 protein. We conducted a case-control study of eighty...

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Bibliographic Details
Main Authors: Svetla Nikolova, Milka Dikova, Dobrin Dikov, Assen Djerov, Gyulnas Dzhebir, Ventseslav Atanasov, Alexey Savov, Ivo Kremensky
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Analytical Cellular Pathology
Online Access:http://dx.doi.org/10.1155/2015/621893
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