A Case of Early Stage Bladder Carcinosarcoma in Late Recurrence of Urothelial Carcinoma after Transurethral Resection
Carcinosarcomas of the urinary bladder are rare biphasic neoplasms, consisting of both malignant epithelial and malignant mesenchymal components, and the prognosis of this tumor is unfavorable in most patients with even possibility of resection of disease. A 77-year-old male with a history of transu...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Case Reports in Urology |
| Online Access: | http://dx.doi.org/10.1155/2018/1405108 |
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| author | Daisaku Hirano Toshiyuki Yoshida Daigo Funakoshi Fuminori Sakurai Shou Ohno Yoshiaki Kusumi |
| author_facet | Daisaku Hirano Toshiyuki Yoshida Daigo Funakoshi Fuminori Sakurai Shou Ohno Yoshiaki Kusumi |
| author_sort | Daisaku Hirano |
| collection | DOAJ |
| description | Carcinosarcomas of the urinary bladder are rare biphasic neoplasms, consisting of both malignant epithelial and malignant mesenchymal components, and the prognosis of this tumor is unfavorable in most patients with even possibility of resection of disease. A 77-year-old male with a history of transurethral resection (TUR) of urothelial carcinoma (UC) of the bladder and adjuvant intravesical chemotherapy with pirarubicin 10 years ago revisited our department with a gross hematuria. Cystoscopy demonstrated an approximately 2.5 cm nonpapillary tumor on the right wall of the bladder. Pelvic MRI showed the tumor without extending the base of the bladder wall. The tumor could be completely removed with TUR. The malignant epithelial elements consisted of high-grade UC and the majority of mesenchymal components were fibrosarcomatous differentiation based on immunohistochemical studies. The tumor could be pathologically also suspected to be an early stage on TUR specimens. Although he has received no additional intervention due to the occurrence of myocardial infarction at three weeks after the TUR, he has been alive with no evidence of recurrence of the disease 27 months after the TUR. Some early stages of bladder carcinosarcoma might have a favorable prognosis without aggressive treatments. |
| format | Article |
| id | doaj-art-1abe8b14558b41b8930a914db0e9b410 |
| institution | Kabale University |
| issn | 2090-696X 2090-6978 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Urology |
| spelling | doaj-art-1abe8b14558b41b8930a914db0e9b4102025-02-03T01:11:32ZengWileyCase Reports in Urology2090-696X2090-69782018-01-01201810.1155/2018/14051081405108A Case of Early Stage Bladder Carcinosarcoma in Late Recurrence of Urothelial Carcinoma after Transurethral ResectionDaisaku Hirano0Toshiyuki Yoshida1Daigo Funakoshi2Fuminori Sakurai3Shou Ohno4Yoshiaki Kusumi5Department of Urology, Higashimatsuyama Municipal Hospital, Higashimatsuyama 355-0041, JapanDepartment of Urology, Higashimatsuyama Municipal Hospital, Higashimatsuyama 355-0041, JapanDepartment of Urology, Nihon University School of Medicine, Tokyo 173-8610, JapanDepartment of Urology, Nihon University School of Medicine, Tokyo 173-8610, JapanDepartment of Urology, Kawaguchi Municipal Medical Center, Kawaguchi 333-0833, JapanDepartment of Pathology, Nihon University School of Medicine, Tokyo 173-8610, JapanCarcinosarcomas of the urinary bladder are rare biphasic neoplasms, consisting of both malignant epithelial and malignant mesenchymal components, and the prognosis of this tumor is unfavorable in most patients with even possibility of resection of disease. A 77-year-old male with a history of transurethral resection (TUR) of urothelial carcinoma (UC) of the bladder and adjuvant intravesical chemotherapy with pirarubicin 10 years ago revisited our department with a gross hematuria. Cystoscopy demonstrated an approximately 2.5 cm nonpapillary tumor on the right wall of the bladder. Pelvic MRI showed the tumor without extending the base of the bladder wall. The tumor could be completely removed with TUR. The malignant epithelial elements consisted of high-grade UC and the majority of mesenchymal components were fibrosarcomatous differentiation based on immunohistochemical studies. The tumor could be pathologically also suspected to be an early stage on TUR specimens. Although he has received no additional intervention due to the occurrence of myocardial infarction at three weeks after the TUR, he has been alive with no evidence of recurrence of the disease 27 months after the TUR. Some early stages of bladder carcinosarcoma might have a favorable prognosis without aggressive treatments.http://dx.doi.org/10.1155/2018/1405108 |
| spellingShingle | Daisaku Hirano Toshiyuki Yoshida Daigo Funakoshi Fuminori Sakurai Shou Ohno Yoshiaki Kusumi A Case of Early Stage Bladder Carcinosarcoma in Late Recurrence of Urothelial Carcinoma after Transurethral Resection Case Reports in Urology |
| title | A Case of Early Stage Bladder Carcinosarcoma in Late Recurrence of Urothelial Carcinoma after Transurethral Resection |
| title_full | A Case of Early Stage Bladder Carcinosarcoma in Late Recurrence of Urothelial Carcinoma after Transurethral Resection |
| title_fullStr | A Case of Early Stage Bladder Carcinosarcoma in Late Recurrence of Urothelial Carcinoma after Transurethral Resection |
| title_full_unstemmed | A Case of Early Stage Bladder Carcinosarcoma in Late Recurrence of Urothelial Carcinoma after Transurethral Resection |
| title_short | A Case of Early Stage Bladder Carcinosarcoma in Late Recurrence of Urothelial Carcinoma after Transurethral Resection |
| title_sort | case of early stage bladder carcinosarcoma in late recurrence of urothelial carcinoma after transurethral resection |
| url | http://dx.doi.org/10.1155/2018/1405108 |
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