The role of transcytosis in the blood-retina barrier: from pathophysiological functions to drug delivery

The role of transcytosis in the blood-retina barrier: from pathophysiological functions to drug delivery

The blood-retina barrier (BRB) serves as a critical interface that separates the retina from the circulatory system, playing an essential role in preserving the homeostasis of the microenvironment within the retina. Specialized tight junctions and limited vesicle trafficking restrict paracellular an...

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Bibliographic Details
Main Authors: Chun-Lin Zhang, Jing-Jie Ma, Xiang Li, Hai-Qing Yan, Yong-Kun Gui, Zhi-Xin Yan, Ming-Feng You, Ping Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Pharmacology
Subjects:
transcytosis
blood-retina barrier
barrier function
vascular leakage
drug delivery
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1565382/full
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