A Rare Case of Wolfram Syndrome Presenting With Tuberculous Meningitis: A Case Report

ABSTRACT Wolfram syndrome is an extremely rare condition composed of a tetrad of diabetes insipidus, diabetes mellitus, optic atrophy, and deafness. When concurrently presenting with another condition, such as tuberculous meningitis, the widespread range of resulting symptoms delays the establishmen...

Full description

Saved in:
Bibliographic Details
Main Authors: Nabiha Khan, Muhammad Usama Ashraf, Sadia Khan, Allahdad Khan, Humna Shahzad, Mudasira Habib, Aseel Kamal
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Clinical Case Reports
Subjects:
Online Access:https://doi.org/10.1002/ccr3.70116
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832589890446950400
author Nabiha Khan
Muhammad Usama Ashraf
Sadia Khan
Allahdad Khan
Humna Shahzad
Mudasira Habib
Aseel Kamal
author_facet Nabiha Khan
Muhammad Usama Ashraf
Sadia Khan
Allahdad Khan
Humna Shahzad
Mudasira Habib
Aseel Kamal
author_sort Nabiha Khan
collection DOAJ
description ABSTRACT Wolfram syndrome is an extremely rare condition composed of a tetrad of diabetes insipidus, diabetes mellitus, optic atrophy, and deafness. When concurrently presenting with another condition, such as tuberculous meningitis, the widespread range of resulting symptoms delays the establishment of diagnosis and treatment, which results in increased patient morbidity.
format Article
id doaj-art-1aaa8bdabc6c4a359baf102848c29269
institution Kabale University
issn 2050-0904
language English
publishDate 2025-01-01
publisher Wiley
record_format Article
series Clinical Case Reports
spelling doaj-art-1aaa8bdabc6c4a359baf102848c292692025-01-24T05:08:46ZengWileyClinical Case Reports2050-09042025-01-01131n/an/a10.1002/ccr3.70116A Rare Case of Wolfram Syndrome Presenting With Tuberculous Meningitis: A Case ReportNabiha Khan0Muhammad Usama Ashraf1Sadia Khan2Allahdad Khan3Humna Shahzad4Mudasira Habib5Aseel Kamal6Department of Medicine Punjab Medical College Faisalabad PakistanDepartment of Medicine Punjab Medical College Faisalabad PakistanDepartment of Radiology Nishtar Medical University Multan PakistanDepartment of Medicine Nishtar Medical University Multan PakistanDepartment of Medicine Nishtar Medical University Multan PakistanDepartment of Radiology Nishtar Medical University Multan PakistanFaculty of Medicine University of Gezira Faculty of Medicine Wad Madani SudanABSTRACT Wolfram syndrome is an extremely rare condition composed of a tetrad of diabetes insipidus, diabetes mellitus, optic atrophy, and deafness. When concurrently presenting with another condition, such as tuberculous meningitis, the widespread range of resulting symptoms delays the establishment of diagnosis and treatment, which results in increased patient morbidity.https://doi.org/10.1002/ccr3.70116blindnessdeafnessdiabetes insipidusdiabetes mellitusDIDMOADWolfram syndrome
spellingShingle Nabiha Khan
Muhammad Usama Ashraf
Sadia Khan
Allahdad Khan
Humna Shahzad
Mudasira Habib
Aseel Kamal
A Rare Case of Wolfram Syndrome Presenting With Tuberculous Meningitis: A Case Report
Clinical Case Reports
blindness
deafness
diabetes insipidus
diabetes mellitus
DIDMOAD
Wolfram syndrome
title A Rare Case of Wolfram Syndrome Presenting With Tuberculous Meningitis: A Case Report
title_full A Rare Case of Wolfram Syndrome Presenting With Tuberculous Meningitis: A Case Report
title_fullStr A Rare Case of Wolfram Syndrome Presenting With Tuberculous Meningitis: A Case Report
title_full_unstemmed A Rare Case of Wolfram Syndrome Presenting With Tuberculous Meningitis: A Case Report
title_short A Rare Case of Wolfram Syndrome Presenting With Tuberculous Meningitis: A Case Report
title_sort rare case of wolfram syndrome presenting with tuberculous meningitis a case report
topic blindness
deafness
diabetes insipidus
diabetes mellitus
DIDMOAD
Wolfram syndrome
url https://doi.org/10.1002/ccr3.70116
work_keys_str_mv AT nabihakhan ararecaseofwolframsyndromepresentingwithtuberculousmeningitisacasereport
AT muhammadusamaashraf ararecaseofwolframsyndromepresentingwithtuberculousmeningitisacasereport
AT sadiakhan ararecaseofwolframsyndromepresentingwithtuberculousmeningitisacasereport
AT allahdadkhan ararecaseofwolframsyndromepresentingwithtuberculousmeningitisacasereport
AT humnashahzad ararecaseofwolframsyndromepresentingwithtuberculousmeningitisacasereport
AT mudasirahabib ararecaseofwolframsyndromepresentingwithtuberculousmeningitisacasereport
AT aseelkamal ararecaseofwolframsyndromepresentingwithtuberculousmeningitisacasereport
AT nabihakhan rarecaseofwolframsyndromepresentingwithtuberculousmeningitisacasereport
AT muhammadusamaashraf rarecaseofwolframsyndromepresentingwithtuberculousmeningitisacasereport
AT sadiakhan rarecaseofwolframsyndromepresentingwithtuberculousmeningitisacasereport
AT allahdadkhan rarecaseofwolframsyndromepresentingwithtuberculousmeningitisacasereport
AT humnashahzad rarecaseofwolframsyndromepresentingwithtuberculousmeningitisacasereport
AT mudasirahabib rarecaseofwolframsyndromepresentingwithtuberculousmeningitisacasereport
AT aseelkamal rarecaseofwolframsyndromepresentingwithtuberculousmeningitisacasereport